Prescribing patterns of anticoagulants in patients with atrial fibrillation in primary care
Introduction. Anticoagulants have the key role in prevention of thromboembolism including ischemic stroke, in patients with non-valvular atrial fibrillation (NVAF). The European Association of Cardiology (ESC) recommends new oral anticoagulant drugs (NOACs) as first choice therapy because of approved effectiveness and safety profile compared to vit...
By Nevena Todorović, Nataša Pilipović-Broćeta, Aleksandra Lukić, Brankica Marković, Verica Prodanović
Application of hyperthermic intraperitoneal chemotherapy at the University Clinical Center of Republic of Srpska
Introduction. Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is an advanced treatment modality for peritoneal malignancies, including ovarian cancer, appendix adenocarcinoma, colorectal cancer, and peritoneal metastases. This approach offers potential benefits in managing these complex conditions.Methods...
By Zoran G. Aleksić, Dragan Tomić, Velimir Škrbić, Nenad Jaćimović, Miroslav Popović, Sladibor Lakić
Neuropathic pain in diabetic peripheral neuropathy and chronic low back pain syndrome: prevalence and characteristics
Introduction. Neuropathic pain (NP) is presented with a variety of symptoms, including “positive” (e.g., spontaneous pain, paresthesia, dysesthesia, allodynia, hyperalgesia, tingling, burning) and “negative” (e.g., numbness and loss of sensation) features. The most common causes are diabetic peripheral neuropathy (DPN) and c...
By Zoran Vukojević, Aleksandra Dominović Kovačević, Sanja Grgić, Daliborka Tadić, Srdjan Mavija
Evaluation of Clinical Profiles in Patients with Benign Pituitary Tumors
Introduction. Benign pituitary tumors are a heterogeneous group of neoplasms with varying clinical presentations depending on their hormonal activity, size, and mass effects. These tumors can cause significant morbidity due to endocrine dysfunction and compression of adjacent structures. Understanding their clinical characteristics is essential for...
By Aleksandra Marković, Tamara Dojčinović, Milena Brkić, Tamara Popović Perić
Production of chemokines by mesenchymal stromal cells established from inflamed human gingiva and its modulation by lipopolysaccharide
Introduction. The role of gingiva-derived stromal cells (GMSCs) in chronic periodontitis is poorly understood. Since GMSCs modulate the inflammatory and immune responses this study aimed to investigate the production of chemokines by GMSCs established from chronic periodontitis tissue under basal conditions and after stimulation with lipopolysaccha...
By Marina Radanović, Miodrag Čolić
Swelling of the optic nerve head due to the coexistence of idiopathic intracranial hypertension and optic nerve drusen
Introduction. Optic nerve head drusen (ONHD) is one of the most common congenital disorder of the optic nerve with prevalence from 0,5-2% in general population. Idiopathic intracranial hypertension is a condition that occurs in children, unlike adults, regardless of gender or the presence of obesity. Both conditions in children present on the eye a...
By Željko Maraš, Tanja Kalezić, Bojan Joksimović, Radmila Balaban Djurević
Evolution of hospitalized COVID-19 cases with emphasis on the first pandemic year: experience from the University Clinical Center of Republic of Srpska
Introduction. Infection caused by the novel coronavirus (SARSCoV-2) emerged in 2019 in China and rapidly spread worldwide. This highly contagious virus is transmitted primarily through respiratory droplets and may lead to Severe Acute Respiratory Syndrome (SARS). The World Health Organization (WHO) declared Coronavirus Disease 2019 (COVID-19) a glo...
By Nataša Janjić, Goran Bokan, Uroš Kalajdžić, Antonija Verhaz, Slavica Zeljković, Zoran Mavija
Association of parameters of ovarian hormonal hyperstimulation with assisted reproductive technology outcomes in infertile women
Introduction. This study analyzed the factors influencing the outcome of assisted reproductive technology (ART) in women with infertility issues. The investigation focused on endometrial thickness, the number of retrieved oocytes, and the number of obtained embryos as potential predictors of ART success.Method. A health-epidemiological questionnair...
By Daniela Telebak, Djordje Čekrlija, Milena Todorović, Slobodan Stanić, Dalibor Mihajlović
Low prevalence of use and negative attitudes toward oral contraceptive pills among female students at the University of East Sarajevo
Introduction. Oral contraceptive pills (OCP) are the most widely used form of reversible contraception globally, although their prevalence of use varies across regions. In Bosnia and Herzegovina, particularly among young women, there remains a significant gap in knowledge regarding sexual and reproductive health, including contraception. Low level ...
By Isidora Skorup, Dragana Sokolović, Ana Pejčić, Branislava Ćurčić, Milica Radanovic, Maja Radović, Dragana Erbez, Dragana Drakul
Early and long-term outcomes after coronary artery bypass grafting using saphenous vein grafts
Introduction. Coronary Artery Bypass Grafting (CABG) remains the cornerstone of surgical myocardial revascularization. Despite major technical refinements and the increasing use of arterial conduits, saphenous vein grafts (SVGs) continue to play a vital role but remain vulnerable to long-term occlusion. The aim of the study was to evaluate early an...
By Andjela Božić, Aleksandar Redžek