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Association of parameters of ovarian hormonal hyperstimulation with assisted reproductive technology outcomes in infertile women

By
Daniela Telebak ,
Daniela Telebak
Contact Daniela Telebak

Department of Nursing and Health , College of Health Sciences, College of Health Sciences , Doboj , Bosnia and Herzegovina

Djordje Čekrlija Orcid logo ,
Djordje Čekrlija

Department of Psychology, Faculty of Philosophy, University of Banja Luka , Banja Luka , Bosnia and Herzegovina

Milena Todorović ,
Milena Todorović

Department of Nursing and Health Care, College of Health Sciences, College of Health Sciences , Doboj , Bosnia and Herzegovina

Slobodan Stanić ,
Slobodan Stanić

Department of Nursing and Health Care, College of Health Sciences, College of Health Sciences , Doboj , Bosnia and Herzegovina

Dalibor Mihajlović Orcid logo
Dalibor Mihajlović

Department of Emergency Medicine, Faculty of Medicine, University of Banja Luka , Banja Luka , Bosnia and Herzegovina

Editor: Siniša Ristić

Abstract

Introduction. This study analyzed the factors influencing the outcome of assisted reproductive technology (ART) in women with infertility issues. The investigation focused on endometrial thickness, the number of retrieved oocytes, and the number of obtained embryos as potential predictors of ART success.
Method. A health-epidemiological questionnaire of general data was created for the purposes of this study. Various statistical methods were applied for data analysis. Descriptive statistical parameters for the observed parameters were pre
sented, including the arithmetic mean (M), standard deviation (SD), skewness (Sk), and kurtosis (Ku), to examine deviations from the normal distribution. Multiple regression analysis was applied to investigate the relationships of the independent variables with the dependent variable.
Results. The study included 100 women of reproductive age. Endometrial thickness was not a significant predictor of ART 
outcome. Conversely, the number of retrieved oocytes and the number of obtained embryos were identified as significant predictors of ART success. Participants with positive ART outcomes demonstrated a lower number of retrieved oocytes 
but a higher number of obtained embryos.
Conclusion. These findings highlight the importance of embryo quality in the implantation process. Further research is 
needed to better understand this dynamic and to improve infertility treatments.

Author Contributions

Conceptualization, D.T.; Data curation, D.T. and D.Č.; Formal Analysis, D.T., D.Č., M.T., S.S. and D.M.; Funding acquisition, D.T.; Investigation, D.T. and D.Č.; Methodology, D.T. and D.Č.; Project administration, D.T.; Resources, D.T.; Software, D.T. and D.Č.; Supervision, D.T., M.T., S.S. and D.M.; Validation, D.T., M.T., S.S. and D.M.; Visualization, D.T.; Writing – original draft, D.T.; Writing – review & editing, D.T. All authors have read and agreed to the published version of the manuscript.

Citation

Funding Statement

This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

Authors retain copyright. This work is licensed under a Creative Commons Attribution 4.0 International License. Creative Commons License

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