Introduction. Breast cancer is the most common malignancy in women and a leading cause of cancer mortality. The HR-positive/HER2-negative subtype accounts for most cases and is characterized by initial endocrine sensitivity followed by resistance. This study aimed to map and interpret randomized clinical trial evidence on the efficacy and safe...

By SANJA STOJANOVIĆ GAGOVIĆ, NIKOLINA DUKIĆ, JELENA VLADIČIĆ MAŠIĆ, DRAGANA STUPAR, NEMANJA KOVAČ, SNEŽANA ZEČEVIĆ

Introduction. Vitamin D deficiency is common worldwide and has been associated with disturbances in glucose metabolism, although evidence remains inconsistent. This study evaluated serum 25(OH)D levels and their crude associations with glycemic control and chronic diabetic complications in patients with type 2 diabetes mellitus (T2DM). Methods. Th...

By IVONA RISOVIĆ, ALEKSANDRA MARKOVIĆ, MARIJANA KOVAČEVIĆ, MIRJANA GNJATIĆ, MILENA BRKIĆ

Introduction. The most common malignant facial skin tumors are basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma. Surgical excision remains the gold standard of treatment, followed by reconstruction of the resulting defect. The aims of this study were to present reconstructive options for facial defects following excision of m...

By SINIŠA KOJIĆ, HELENA MARIĆ KUJUNDŽIĆ, BOJAN KUJUNDŽIĆ, RADE MILETIĆ, MIROSLAV OBRENOVIĆ, NENAD LALOVIĆ

Introduction. Effective rehabilitation is essential for recovery after total knee arthroplasty (TKA), yet the magnitude of benefit from intensive inpatient programs remains incompletely defined. This work aimed to evaluate the effects of a standardized 21-day inpatient rehabilitation program on pain, functional status, and health-related quali...

By TATJANA NOŽICA RADULOVIĆ, MAJA VUČKOVIĆ, DRAGANA KOŽUL, STANISLAV PALIJA, MONIKA JELAČIĆ, VEDRAN MILOJEVIĆ

Introduction. Point-of-care ultrasound (POCUS) is increasingly recognized as an extension of the physical examination, enhancing bedside diagnostic accuracy and real-time clinical decision-making. Although widely integrated into medical education and practice internationally, its routine implementation in Bosnia and Herzegovina remains inconsistent...

By ŽELJKA POPOVIĆ, SINIŠA RISTIĆ, ZAGORKA BLAGOJEVIC PAVLOVIĆ

Introduction. Salivary uric acid (UA) has been proposed as a non-invasive biomarker of oxidative stress and neuroinflammation in psychiatric disorders. This scoping review aimed to map evidence on salivary UA in psychiatric conditions and during acute psychosocial stress, identify methodologies, and highlight gaps. Methods. PubMed was searched...

By MIODRAG KOVAČEVIĆ, BRANKA KOVAČEVIĆ, SNEŽANA MARJANOVIĆ, DRAGANA PUHALO SLADOJE, MILE JEVTIC

Introduction. Type 2 diabetes mellitus is associated with an increased risk of coronary artery disease, which frequently remains clinically silent. Myocardial perfusion imaging with single-photon emission computed tomography is widely used for the detection of myocardial ischemia and risk stratification, but its prognostic value in asymptomatic dia...

By SINIŠA STANKOVIĆ, DRAGANA ŠOBIĆ-ŠARANOVIĆ, VALENTINA SOLDAT-STANKOVIĆ, VERA ARTIKO, ZVEZDANA RAJKOVAČA, GOSTIMIR MIKAČ, NATAŠA EGELJIĆ-MIHAILOVIĆ, TANJA ILIČIĆ