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30.06.2022.

Original Scientific Article

Magnetic resonance imaging of the heart as a method of long-term monitoring of right heart function after tetralogy of Fallot surgery

By Biljana Milinković, Jelena Milić, Dejan Bokonjić, Verica Prodanović, Bojan Joksimović, Siniša Ristić

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A Publication of University of East Sarajevo, Faculty of Medicine Foča

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Edited by:

Prof. Siniša Ristić MD, PhD

Vol 13, No 1 (2022):

Biomedicinska istraživanja

Published: 30.06.2022.

Articles

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01.12.2018. Original Scientific Article
Impact of elapsed time between first symptoms and diagnosis of celiac disease on psycho-physical functioning and social life of children and adolescents

By Biljana Stojanović-Jovanović, Stevan Jovanović, Biljana Vuletić

Introduction. Celiac disease is an autoimmune disease resulting from an inadequate immune response to gluten in genetically predisposed individuals as a result of consuming gluten and other related proteins present in wheat, rye, barley and oats. The only cure for this specific disease is a strict, carefully controlled and lifelong gluten-free diet. The aim of the study was to evaluate whether the elapsed time between the onset of the first symptoms and the diagnosis of celiac disease affected the psycho-physical functioning and social life of children and adolescents.

Methods. The study involved 116 respondents (39 of them were males), aged 8-18 years, who were diagnosed with celiac disease. The Documentation Sheet and the Celiac-Specific Pediatric Health-Related Instrument (CDPQOL), measuring the psycho-physical functioning and social life, were used in the study.

Results. 50% of subjects, aged ≤ 2 years, were diagnosed with celiac disease. 48.28% of them were diagnosed with the disease within three months after the symptom onset. In respondents with celiac disease, aged 8-12 years, there was no statistically significant difference between the psycho-physical functioning and social life and the elapsed time between the first symptoms and the established diagnosis. In subjects aged 13-18 years, using CDPQOL, a statistically significant difference was found in the following domains: school functioning, going out and social events, self-confidence. Furthermore, there was a statistically significant difference between total CDPQOL score and the elapsed time between the first symptoms and the established diagnosis.

Conclusion. The elapsed time between the first symptoms and the established diagnosis significantly affects the psycho-physical functioning and social life of subjects aged 13-18 years, but it does not affect the psycho-physical functioning and social life of the younger respondents. This is to confirm the importance of early diagnosis and treatment initiation.

01.12.2020. Reviews
Vitamin D and atherosclerosis

By Vesna Lazić, Biljana Mijović, Miloš Maksimović, Olivera Rašević, Maida Mulić, Maja Vuković

Cardiovascular diseases rank first on the mortality list globally or 31%. The basic measure of prevention in accordance with the recommendations of the World Health Organization is a change in risk lifestyle in terms of diet, physical activity, tobacco and alcohol consumption. Vitamin D was previously recognized as a regulator of calcium and phosphorus ratio, bone remodeling or the main controller of skeletal pathophysiology. However, vitamin D enjoys great interest in clinical and epidemiological research in terms of its possible impact on reducing the risk of cardiovascular diseases. Among other things, vitamin D deficiency is associated with an increased risk of endothelial dysfunction. Although the deficiency has been identified as a risk marker for cardiovascular diseases, the mechanism of action of vitamin D on the path from endothelial dysfunction to cardiovascular diseases has not been fully revealed. The findings in this segment of activity of vitamin D would be significant in terms of reducing morbidity and mortality from cardiovascular diseases.

01.12.2020. Original Scientific Article
The knowledge of nurses about prevention of infections caused by the bacteria Clostridium difficile

By Ivana Miljković, Amajla Topuz

Introduction. Celiac disease is an autoimmune disease resulting from an inadequate immune response to gluten in genetically predisposed individuals as a result of consuming gluten and other related proteins present in wheat, rye, barley and oats. The only cure for this specific disease is a strict, carefully controlled and lifelong gluten-free diet. The aim of the study was to evaluate whether the elapsed time between the onset of the first symptoms and the diagnosis of celiac disease affected the psycho-physical functioning and social life of children and adolescents.

Methods. The study involved 116 respondents (39 of them were males), aged 8-18 years, who were diagnosed with celiac disease. The Documentation Sheet and the Celiac-Specific Pediatric Health-Related Instrument (CDPQOL), measuring the psycho-physical functioning and social life, were used in the study.

Results. 50% of subjects, aged ≤ 2 years, were diagnosed with celiac disease. 48.28% of them were diagnosed with the disease within three months after the symptom onset. In respondents with celiac disease, aged 8-12 years, there was no statistically significant difference between the psycho-physical functioning and social life and the elapsed time between the first symptoms and the established diagnosis. In subjects aged 13-18 years, using CDPQOL, a statistically significant difference was found in the following domains: school functioning, going out and social events, self-confidence. Furthermore, there was a statistically significant difference between total CDPQOL score and the elapsed time between the first symptoms and the established diagnosis.

Conclusion. The elapsed time between the first symptoms and the established diagnosis significantly affects the psycho-physical functioning and social life of subjects aged 13-18 years, but it does not affect the psycho-physical functioning and social life of the younger respondents. This is to confirm the importance of early diagnosis and treatment initiation.

01.12.2012. Original Scientific Article
Sensibility of tactile discrimination between the fingers of the dominant and non-dominant hands

By Slavko Grbić, Marinko Domuzin, Aleksandra Grbić, Olivera P Spasojević, Zoran Obradović

01.12.2011. Original Scientific Article
Učešće medicinskih sestara u rješavanju akutnih komplikacija dijabetesa

By Natalija Hadživuković, Mirjana Stamenović, Ljiljana Milović, Jelena Pavlović, Sandra Joković

01.12.2013. Original Scientific Article
Uticaj porodičnih i psihopatoloških činilaca na silovanje

By Milan Novaković, Milan Kulić, Vesna Despotovic, Joana Maric Burmazovic, Snežana Medinica, Dragan Jovanović

30.06.2022. Original Scientific Article
Voice condition assessment and the effect of rehabilitation in vocal professionals

By Mila Bunijevac, Zlatko Maksimović, Andrijana Mikić

Current issue

30.06.2022. Original Scientific Article
Magnetic resonance imaging of the heart as a method of long-term monitoring of right heart function after tetralogy of Fallot surgery

By Biljana Milinković, Jelena Milić, Dejan Bokonjić, Verica Prodanović, Bojan Joksimović, Siniša Ristić

30.06.2022. Original Scientific Article
Influence of smoking on voice quality

By Bojana Vuković, Slađana Ćalasan, Andrea Vegar

30.06.2022. Original Scientific Article
Reading ability of young school-age children

By Mile Vuković, Rada Reljić Trivković, Slađana Ćalasan

30.06.2022. Original Scientific Article
Voice condition assessment and the effect of rehabilitation in vocal professionals

By Mila Bunijevac, Zlatko Maksimović, Andrijana Mikić

Recent issues

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Most read

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01.12.2020. Reviews
Vitamin D and atherosclerosis

By Vesna Lazić, Biljana Mijović, Miloš Maksimović, Olivera Rašević, Maida Mulić, Maja Vuković

Cardiovascular diseases rank first on the mortality list globally or 31%. The basic measure of prevention in accordance with the recommendations of the World Health Organization is a change in risk lifestyle in terms of diet, physical activity, tobacco and alcohol consumption. Vitamin D was previously recognized as a regulator of calcium and phosphorus ratio, bone remodeling or the main controller of skeletal pathophysiology. However, vitamin D enjoys great interest in clinical and epidemiological research in terms of its possible impact on reducing the risk of cardiovascular diseases. Among other things, vitamin D deficiency is associated with an increased risk of endothelial dysfunction. Although the deficiency has been identified as a risk marker for cardiovascular diseases, the mechanism of action of vitamin D on the path from endothelial dysfunction to cardiovascular diseases has not been fully revealed. The findings in this segment of activity of vitamin D would be significant in terms of reducing morbidity and mortality from cardiovascular diseases.

01.12.2020. Original Scientific Article
The knowledge of nurses about prevention of infections caused by the bacteria Clostridium difficile

By Ivana Miljković, Amajla Topuz

01.12.2012. Original Scientific Article
Sensibility of tactile discrimination between the fingers of the dominant and non-dominant hands

By Slavko Grbić, Marinko Domuzin, Aleksandra Grbić, Olivera P Spasojević, Zoran Obradović

01.12.2011. Original Scientific Article
Učešće medicinskih sestara u rješavanju akutnih komplikacija dijabetesa

By Natalija Hadživuković, Mirjana Stamenović, Ljiljana Milović, Jelena Pavlović, Sandra Joković

01.12.2018. Original Scientific Article
Impact of elapsed time between first symptoms and diagnosis of celiac disease on psycho-physical functioning and social life of children and adolescents

By Biljana Stojanović-Jovanović, Stevan Jovanović, Biljana Vuletić

Introduction. Celiac disease is an autoimmune disease resulting from an inadequate immune response to gluten in genetically predisposed individuals as a result of consuming gluten and other related proteins present in wheat, rye, barley and oats. The only cure for this specific disease is a strict, carefully controlled and lifelong gluten-free diet. The aim of the study was to evaluate whether the elapsed time between the onset of the first symptoms and the diagnosis of celiac disease affected the psycho-physical functioning and social life of children and adolescents.

Methods. The study involved 116 respondents (39 of them were males), aged 8-18 years, who were diagnosed with celiac disease. The Documentation Sheet and the Celiac-Specific Pediatric Health-Related Instrument (CDPQOL), measuring the psycho-physical functioning and social life, were used in the study.

Results. 50% of subjects, aged ≤ 2 years, were diagnosed with celiac disease. 48.28% of them were diagnosed with the disease within three months after the symptom onset. In respondents with celiac disease, aged 8-12 years, there was no statistically significant difference between the psycho-physical functioning and social life and the elapsed time between the first symptoms and the established diagnosis. In subjects aged 13-18 years, using CDPQOL, a statistically significant difference was found in the following domains: school functioning, going out and social events, self-confidence. Furthermore, there was a statistically significant difference between total CDPQOL score and the elapsed time between the first symptoms and the established diagnosis.

Conclusion. The elapsed time between the first symptoms and the established diagnosis significantly affects the psycho-physical functioning and social life of subjects aged 13-18 years, but it does not affect the psycho-physical functioning and social life of the younger respondents. This is to confirm the importance of early diagnosis and treatment initiation.

01.12.2013. Original Scientific Article
Uticaj porodičnih i psihopatoloških činilaca na silovanje

By Milan Novaković, Milan Kulić, Vesna Despotovic, Joana Maric Burmazovic, Snežana Medinica, Dragan Jovanović

30.06.2022. Original Scientific Article
Voice condition assessment and the effect of rehabilitation in vocal professionals

By Mila Bunijevac, Zlatko Maksimović, Andrijana Mikić

01.12.2016. Letter to the editor
Pre-existing arterial microcalcification and arteriovenous fistula failure

By Nenad Petković, Radoslav Gajanin, Ljubica Djukanović

01.12.2015. Original Scientific Article
Kvantitativna analiza magnocelularnog dijela nucleus ruber-a

By Vesna Gajanin, Zdenka Krivokuća, Igor Sladojević, Tatjana Bućma, Mirka Šarović Vukajlović

Uvod. Nucleus ruber zauzima centralni dio retikularne formacije srednjegmozga, od donjeg kraja gornjih kvržica srednjeg mozga do ventralnog talamusa.Vaskularizuju ga grane P1 i P2 segmenta arteriae cerebri posterior, arteriaecommunicans posterior i arteriae choroidea anterior. Ciljevi rada su kvantitativnaanaliza neurona i vaskularne mreže magnocelularnog dijela nucleus ruber-a,kao i ispitivanje uticaja starenja na parametre kvantitativne analize.Metode. Deset srednjih mozgova odraslih lica oba pola je nakon fiksacijeu 10% rastvoru formalina ukalupljeno u parafinu. Zbog lokalizacije magnocelularnogdijela nucleus ruber-a, uzorci srednjih mozgova su presječeni uvisini sredine gornjih kvržica srednjeg mozga i idući kaudalno pravljeni susemiserijski rezovi (1,5,10...50) debljine 4 μm, koji su bojeni Mallory metodom.Pomoću digitalne kamere slikano je intermitentno svako drugo vidno poljepod uvećanjem 400x, a dobijene fotografije su analizirane pomoću programaImageJ, uz korišćenje testnog sistema A 100. Statistička analiza je obavljenauz upotrebu programa SPSS, uz nivo značajnosti razlike od 5%.Rezultati. Prosječne vrijednosti kvantitativnih parametara neurona su iznosile:volumenska gustina 0,018 mm0, površinska gustina 3,56 mm-1 i apsolutnibroj po vidnom polju 35,39. Prosječna volumenska gustina vaskularne mrežemagnocelularnog dijela nucleus ruber-a je 0,014 mm0, površinska gustina 4,19mm-1 i dužinska gustina 90,82 mm-2. Nije postojala korelacija između godinaživota i određivanih kvantitativnih parametara neurona i vaskularne mrežemagnocelularnog dijela nucleus ruber-a.Zaključak. Ispitivani kvantitativni parametri neurona i vaskularne mrežemagnocelularnog dijela nucleus ruber-a se smanjuju sa godinama života, alismanjenje nije statistički značajno.