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30.06.2022.

Original Scientific Article

Magnetic resonance imaging of the heart as a method of long-term monitoring of right heart function after tetralogy of Fallot surgery

By Biljana Milinković, Jelena Milić, Dejan Bokonjić, Verica Prodanović, Bojan Joksimović, Siniša Ristić

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A Publication of University of East Sarajevo, Faculty of Medicine Foča

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A platform for physicians, dentists, health care and special education and rehabilitation professionals

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Prof. Siniša Ristić MD, PhD

Vol 13, No 2 (2022):

Biomedicinska istražavanja

Published: 29.12.2022.

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01.12.2018. Original Scientific Article
Impact of elapsed time between first symptoms and diagnosis of celiac disease on psycho-physical functioning and social life of children and adolescents

By Biljana Stojanović-Jovanović, Stevan Jovanović, Biljana Vuletić

Introduction. Celiac disease is an autoimmune disease resulting from an inadequate immune response to gluten in genetically predisposed individuals as a result of consuming gluten and other related proteins present in wheat, rye, barley and oats. The only cure for this specific disease is a strict, carefully controlled and lifelong gluten-free diet. The aim of the study was to evaluate whether the elapsed time between the onset of the first symptoms and the diagnosis of celiac disease affected the psycho-physical functioning and social life of children and adolescents.

Methods. The study involved 116 respondents (39 of them were males), aged 8-18 years, who were diagnosed with celiac disease. The Documentation Sheet and the Celiac-Specific Pediatric Health-Related Instrument (CDPQOL), measuring the psycho-physical functioning and social life, were used in the study.

Results. 50% of subjects, aged ≤ 2 years, were diagnosed with celiac disease. 48.28% of them were diagnosed with the disease within three months after the symptom onset. In respondents with celiac disease, aged 8-12 years, there was no statistically significant difference between the psycho-physical functioning and social life and the elapsed time between the first symptoms and the established diagnosis. In subjects aged 13-18 years, using CDPQOL, a statistically significant difference was found in the following domains: school functioning, going out and social events, self-confidence. Furthermore, there was a statistically significant difference between total CDPQOL score and the elapsed time between the first symptoms and the established diagnosis.

Conclusion. The elapsed time between the first symptoms and the established diagnosis significantly affects the psycho-physical functioning and social life of subjects aged 13-18 years, but it does not affect the psycho-physical functioning and social life of the younger respondents. This is to confirm the importance of early diagnosis and treatment initiation.

Current issue
29.12.2022. Original Scientific Article
The impact of TP53 and PTEN tumor suppressor genes on response to different breast cancer treatment modalities

By Nikola Tanić, Tatjana Dramićanin, Nejla Ademović, Tijana Tomić, Blagoje Murganić, Zorka Milovanović, Milica Nedeljković, Nasta Tanić

29.12.2022. Original Scientific Article
Deaf and technology: A bibliometric analysis of scientific literature

By Bojana Vuković, Sladjana Ćalasan, Andrea Vegar, Sanja Živanović

29.12.2022. Original Scientific Article
Visual-motor integration of younger school-aged children

By Jelena Milić, Sladjana Djorem, Ana Lukić, Marko Petrović, Bojan Joksimović, Biljana Mijović, Radmila Balaban, Vesna Krstović Spremo, Dajana Nogo Živanović, Veljko Marić

29.12.2022. Original Scientific Article
Stereological analysis of vascular network of subcortical auditory centers

By Tatjana Bućma, Zdenka Krivokuća, Igor Sladojević

29.12.2022. Original Scientific Article
Analysis of CD31 expression and vascular parameters in human placentas from pregnant women with intrauterine growth restriction

By Vesna Ljubojević, Sanja Jovičić, Dragica Draganović, Ljiljana Amidžić, Biljana Vatreš, Nataša Vojinović

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30.06.2022. Original Scientific Article
Voice condition assessment and the effect of rehabilitation in vocal professionals

By Mila Bunijevac, Zlatko Maksimović, Andrijana Mikić

Introduction. The human voice is an important characteristic that enables the distinction of human from other living beings. Otherwise, it represents a picture of a person ́s personality, his health, mental and emotional state. The research aims are to determine the voice characteristics of vocal professionals with diagnosed vocal cord nodules by subjective voice assessment and objective voice measurement before and after vocal rehabilitation.

Methods. This study has involved 25 examinees, aged 23 to 56. The subjective voice assessment was conducted with the Voice Handicap Index - VHI questionnaire and the objective voice measurement by a computerized laboratory for voice analysis ‘’Kay Elemetrics’’. The obtained data were processed using descriptive and analytical statistics.

Results. Before the vocal rehabilitation and the subjective and objective voice measurements, the examinees had greater psychosocial difficulties associated with their voice quality. After two months of vocal rehabilitation, there has been a significant improvement in the voice of all subjects on the VHI scale. A statistically significant and highly statistically significant improvement have been noticed in six out of seven analyzed parameters of vocal A, by the objective measurement of voice. Namely, the obtained values - the percentage of jitter Jitt (%), the percentage of shimmer Shim (%), the relative average perturbation value RAP (%) and the coefficient of fundamental frequency variation - vFo were highly statistically significant (p < 0.01). The VTI - voice turbulence index and the SPI - soft phonation index also improved, the observed difference was statistically significant (p < 0.05), while the observed difference in the FTRI parameter was not statistically significant (p > 0.05).

Conclusion. Vocal rehabilitation has influenced the improvement of the voice quality, which means that the results obtained by objective voice measurements were more in accordance with the results of the subjective voice assessment.

 

01.12.2020. Reviews
Vitamin D and atherosclerosis

By Olivera Rašević, Maida Mulić, Maja Vuković

01.12.2020. Original Scientific Article
The knowledge of nurses about prevention of infections caused by the bacteria Clostridium difficile

By Ivana Miljković, Amajla Topuz

01.12.2012. Original Scientific Article
Sensibility of tactile discrimination between the fingers of the dominant and non-dominant hands

By Olivera P Spasojević, Zoran Obradović

01.12.2011. Original Scientific Article
Učešće medicinskih sestara u rješavanju akutnih komplikacija dijabetesa

By Mirjana Stamenović, Ljiljana Milović

Uvod. Akutne komplikacije dijabetesa predstavljaju akutno nastale metaboličkeporemećaje u čijoj osnovi leže ekstremni poremećaji nivoa glukoze u krvi.Cilj ovog istraživanja je da se ispita učestalost pojave akutnih komplikacijakod oboljelih od dijabetesa koje su nastale kao posljedica loše glikoregulacijei analizira obim i sadržaj sestrinskog rada u rješavanju tih komplikacija.Metode. Istraživanje je izvedeno u periodu septembar-oktobar 2011.godine nainternom odjeljenju u Univerzitetskoj bolnici Foča. U istraživanju su korišćenadva anonimna upitnika kojim su anketirani pacijenti koji boluju od dijabetesai medicinske sestre koje učestvuju u njihovom liječenju.Rezultati. Više od polovine pacijenata (60%) je upoznato sa komplikacijamadijabetesa, a više od dvije trećine (73%) ispitanika zna prepoznati znakehiperglikemije, dok 63% ispitanika zna da su osjećaj mučnine, gladi i klonulostiznaci hipoglikemije. Najveći dio medicinskog osoblja (71%) smatra daje najčešći uzrok komplikacija ne uzimanje terapije, zato više od dvije trećineispitanika (79%) motiviše pacijente da se pridržavaju higijensko-dijetetskogrežima i da redovno uzimaju terapiju.Zaključak. Naši rezultati ukazuju da pacijenti nisu dovoljno upoznati saakutnim komplikacijama dijabetesa, a da je znanje medicinskog osoblja nazadovoljavajućem nivou, mada može da bude još bolje. Zato je neophodnakontinuirana edukacija, kako bolesnika tako i medicinskog osoblja sa ciljemprevencije komplikacija od dijabetesa.

01.12.2018. Original Scientific Article
Impact of elapsed time between first symptoms and diagnosis of celiac disease on psycho-physical functioning and social life of children and adolescents

By Biljana Stojanović-Jovanović, Stevan Jovanović, Biljana Vuletić

01.12.2013. Original Scientific Article
Uticaj porodičnih i psihopatoloških činilaca na silovanje

By Milan Kulić, Vesna Despotovic, Joana Maric Burmazovic, Snežana Medinica

01.12.2015. Original Scientific Article
Kvantitativna analiza magnocelularnog dijela nucleus ruber-a

By Mirka Šarović Vukajlović, Vesna Gajanin, Zdenka Krivokuća, Igor Sladojević, Tatjana Bućma

Uvod. Nucleus ruber zauzima centralni dio retikularne formacije srednjegmozga, od donjeg kraja gornjih kvržica srednjeg mozga do ventralnog talamusa.Vaskularizuju ga grane P1 i P2 segmenta arteriae cerebri posterior, arteriaecommunicans posterior i arteriae choroidea anterior. Ciljevi rada su kvantitativnaanaliza neurona i vaskularne mreže magnocelularnog dijela nucleus ruber-a,kao i ispitivanje uticaja starenja na parametre kvantitativne analize.Metode. Deset srednjih mozgova odraslih lica oba pola je nakon fiksacijeu 10% rastvoru formalina ukalupljeno u parafinu. Zbog lokalizacije magnocelularnogdijela nucleus ruber-a, uzorci srednjih mozgova su presječeni uvisini sredine gornjih kvržica srednjeg mozga i idući kaudalno pravljeni susemiserijski rezovi (1,5,10...50) debljine 4 μm, koji su bojeni Mallory metodom.Pomoću digitalne kamere slikano je intermitentno svako drugo vidno poljepod uvećanjem 400x, a dobijene fotografije su analizirane pomoću programaImageJ, uz korišćenje testnog sistema A 100. Statistička analiza je obavljenauz upotrebu programa SPSS, uz nivo značajnosti razlike od 5%.Rezultati. Prosječne vrijednosti kvantitativnih parametara neurona su iznosile:volumenska gustina 0,018 mm0, površinska gustina 3,56 mm-1 i apsolutnibroj po vidnom polju 35,39. Prosječna volumenska gustina vaskularne mrežemagnocelularnog dijela nucleus ruber-a je 0,014 mm0, površinska gustina 4,19mm-1 i dužinska gustina 90,82 mm-2. Nije postojala korelacija između godinaživota i određivanih kvantitativnih parametara neurona i vaskularne mrežemagnocelularnog dijela nucleus ruber-a.Zaključak. Ispitivani kvantitativni parametri neurona i vaskularne mrežemagnocelularnog dijela nucleus ruber-a se smanjuju sa godinama života, alismanjenje nije statistički značajno.