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30.06.2022.

Original Scientific Articles

Magnetic resonance imaging of the heart as a method of long-term monitoring of right heart function after tetralogy of Fallot surgery

By Biljana Milinković, Jelena Milić, Dejan Bokonjić, Verica Prodanović, Bojan Joksimović, Siniša Ristić

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Edited by:

Prof. Siniša Ristić MD, PhD

Vol 14, No 2 (2023):

Biomedicinska istraživanja

Published: 29.12.2023.

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28.12.2019. Original Scientific Articles
Impact of elapsed time between first symptoms and diagnosis of celiac disease on psycho-physical functioning and social life of children and adolescents

By Biljana Stojanović-Jovanović, Stevan Jovanović, Biljana Vuletić

Introduction. Celiac disease is an autoimmune disease resulting from an inadequate immune response to gluten in genetically predisposed individuals as a result of consuming gluten and other related proteins present in wheat, rye, barley and oats. The only cure for this specific disease is a strict, carefully controlled and lifelong gluten-free diet. The aim of the study was to evaluate whether the elapsed time between the onset of the first symptoms and the diagnosis of celiac disease affected the psycho-physical functioning and social life of children and adolescents.

Methods. The study involved 116 respondents (39 of them were males), aged 8-18 years, who were diagnosed with celiac disease. The Documentation Sheet and the Celiac-Specific Pediatric Health-Related Instrument (CDPQOL), measuring the psycho-physical functioning and social life, were used in the study.

Results. 50% of subjects, aged ≤ 2 years, were diagnosed with celiac disease. 48.28% of them were diagnosed with the disease within three months after the symptom onset. In respondents with celiac disease, aged 8-12 years, there was no statistically significant difference between the psycho-physical functioning and social life and the elapsed time between the first symptoms and the established diagnosis. In subjects aged 13-18 years, using CDPQOL, a statistically significant difference was found in the following domains: school functioning, going out and social events, self-confidence. Furthermore, there was a statistically significant difference between total CDPQOL score and the elapsed time between the first symptoms and the established diagnosis.

Conclusion. The elapsed time between the first symptoms and the established diagnosis significantly affects the psycho-physical functioning and social life of subjects aged 13-18 years, but it does not affect the psycho-physical functioning and social life of the younger respondents. This is to confirm the importance of early diagnosis and treatment initiation.

12.03.2024. Case Reports Online First
Gemination of maxillary incisors in decidous and permanent dentition – a case report

By Isidora Nešković, Aleksandar Anđelković, Duška Blagojević, Sanja Vujkov, Jelena Komšić, Bojan Petrović

Introduction. Shape variations of teeth can be present both in perma nent and in deciduous dentition. Gemination, fusion, concrescention, and ,,twin teeth” are development anomalies. Aim of this article is to show different cases of simultaneous gemination in deciduous denti tion and supernumerary teeth in permanent dentition in upper incisors region.

Case report. A nine-year-old girl, suffering from juvenile idiopathic arthritis, has been sent to the Dental Clinic of Vojvodina. The clinical examination and OPG (orthopantomography) analysis revealed the presence of supernumerary tooth in the region of tooth 51, and also supernumerary tooth in tooth region 11. There was the presence of a cyst in the region 23, which was corresponding to the follicular cyst. The treatment plan included extraction of tooth 51 and supernumer ary tooth, extraction of tooth 52, and control examination after three months with 3D radiography.

Conclusion. Full cooperation between pediatric dentist, oral surgeon and orthodontics is required. Therapy should be focused on balanc ing the occlusion and gaining best aesthetic results. The significance of highlighting the importance of this case lies in its contribution to expanding our understanding of gemination anomalies in the dental f ield. By presenting a rare occurrence involving gemination of maxillary incisors in both deciduous and permanent dentition, this case report offers valuable insights into the clinical manifestations, diagnostic ap proaches and treatment strategies associated with this condition.

Current issue
07.11.2023. Original Scientific Articles
Knowledge and attitudes of employees at the Faculty of Medicine Foča about the concept and ethical issues in genetics

By Nikolina Elez-Burnjaković, Milena Dubravac Tanasković, Milan Kulić, Radmila Balaban Đurević, Aleksandar Tanović, Kristina Drašković Mališ, Biljana Vasiljević, Bojan Joksimović

18.12.2023. Original Scientific Articles
Sex-dependent differences in patients treated with regular hemodialysis

By Ljubica Mitev Prokopović, Miodrag Sokolović, Branimir Haviža Lilić, Miomir Prokopović

20.11.2023. Original Scientific Articles
Risk factors for the emergence of frailty in elderly persons in Bosnia and Herzegovina

By Natalija Hadživuković, Jelena Pavlović, Srdjan Živanović, Sandra Matović, Srdjan Mašić, Dragan Spaić, Olivera Kalajdžić, Ljubiša Kucurski, Mile Despotović

14.11.2023. Original Scientific Articles
Methodological pluralism or multimethod research in health and medical sciences

By Srdjan Živanović, Jelena Pavlović, Natalija Hadživuković, Sandra Matović, Olivera Kalajdžić, Bojana Vuković, Ljubiša Kucurski

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01.12.2011. Original Scientific Articles
Dijagnostika fokalnih promjena u jetri

By Zoran Terzić, Branko Brmbolić, Miloš Korać, Boban Đorđević, Dragica Terzić, Bogdanka Andrić, Siniša Ristić

Uvod. Patološki procesi u jetri mogu biti difuznog karaktera (zapaljenski,metaboličke bolesti, hematološke bolesti, toksične bolesti) i fokalne (zapaljenske,parazitarne i tumorske). Cilj rada je prikaz fokalnih promjena u jetrinomparenhimu nakon ultrazvučne, laparaskopske i patohistološke dijagnostike.Metode. Retrospektivno-prospektivnim ispitivanjem je obuhvaćeno 147punoljetnih pacijenata oba pola. Fokalne promjene jetrinog tkiva su sagledaneultrazvučnom, laparoskopskom i patohistološkom dijagnostikom.Rezultati. Osnovne karakteristike ispitanika: muškaraca 71 i žena 76 sanajvećim brojem pacijenata (102 - 70%) životne dobi između 40 i 70 godina,sa ravnomjernom distribucijom za svakih deset godina starosti. Međutim,neobično je veliki broj pacijenata ženskog pola registrovan u četvrtoj decenijiživota, čak 14 (9,5%) od ukupnog broja ispitanika, odnosno 18% odispitanika ženskog pola. Metastaze čine 104 (71%) svih fokalnih lezija jetre.U većini slučajeva radilo se o metastazama karcinoma dojke. Iako najčešćeimaju tipičnu ultrazvučnu prezentaciju, metastaze u jetri mogu da daju širokspektar različitih ultrazvučnih slikaZaključak. Najčešće fokalne promjene u jetri su metastaze adenokarcinoma.Samo 3 (2%) fokalne promjene dijagnostikovane ultrazvukom nisu potvrđenekao fokalne laparoskopskom tehnikom i patohistološkom analizom tkiva jetre.

30.06.2022. Original Scientific Articles
Voice condition assessment and the effect of rehabilitation in vocal professionals

By Mila Bunijevac, Zlatko Maksimović, Andrijana Mikić

28.06.2021. Reviews
Vitamin D and atherosclerosis

By Olivera Rašević, Maida Mulić, Maja Vuković, Vesna Lazić, Biljana Mijović, Miloš Maksimović

28.06.2021. Original Scientific Articles
The knowledge of nurses about prevention of infections caused by the bacteria Clostridium difficile

By Ivana Miljković, Amajla Topuz

30.06.2022. Original Scientific Articles
Magnetic resonance imaging of the heart as a method of long-term monitoring of right heart function after tetralogy of Fallot surgery

By Biljana Milinković, Jelena Milić, Dejan Bokonjić, Verica Prodanović, Bojan Joksimović, Siniša Ristić

Introduction. Cardiac magnetic resonance imaging (CMR) is considered the reference diagnostic method for quantifying right ventricular size and function, and pulmonary regurgitation in patients with tetralogy of Fallot surgery. The aim of this paper is to confirm the importance of magnetic resonance continuous postoperative monitoring of right and left heart function parameters as a diagnostic method that provides the most precise and accurate assessment.

Methods. The prospective observational study included subjects with TOF surgery who were diagnosed with residual morphological and/or functional disorders on control postoperative echocardiographic examinations. All subjects underwent magnetic resonance imaging of the heart on a 1.5 T scanner with dedicated coils for the heart surface according to the standard protocol for a period of one year from the beginning of the study. Criteria for exclusion from the study were: significant residual pulmonary stenosis, condition after pulmonary valve replacement, existence of residual shunt lesions, contraindications for cardiac magnetic resonance imaging (pacemaker, ICD, claustrophobia). Depending on the time elapsed since the tetralogy of Fallot surgery, the subjects were divided into groups: more than 15 years, 11−15 years, 6−10 years, less than 5 years.

Results. The study included 131 subjects with an average age of 24.18 ± 11.57 years with complete correction of TOF. Intergroup differences in values of right ventricular enddiastolic volume, right ventricular ejection fraction, and left ventricular ejection fraction were demonstrated, but there was no statistically significant intergroup difference in values of pulmonary regurgitation fraction. The negative interaction of the right and left ventricles intensifies during the years of follow-up of patients after TOF surgery, which is especially true fifteen years after surgery.

Conclusion. CMR has the most significant role in research efforts aimed at improving the outcomes of operated patients with tetralogy of Fallot.

01.12.2012. Original Scientific Articles
Sensibility of tactile discrimination between the fingers of the dominant and non-dominant hands

By Olivera P Spasojević, Zoran Obradović, Slavko Grbić, Marinko Domuzin, Aleksandra Grbić

28.06.2012. Original Scientific Articles
Učešće medicinskih sestara u rješavanju akutnih komplikacija dijabetesa

By Mirjana Stamenović, Ljiljana Milović, Natalija Hadživuković, Jelena Pavlović, Sandra Joković

28.12.2019. Original Scientific Articles
Impact of elapsed time between first symptoms and diagnosis of celiac disease on psycho-physical functioning and social life of children and adolescents

By Biljana Stojanović-Jovanović, Stevan Jovanović, Biljana Vuletić

28.06.2014. Original Scientific Articles
Uticaj porodičnih i psihopatoloških činilaca na silovanje

By Milan Kulić, Vesna Despotovic, Joana Maric Burmazovic, Snežana Medinica, Milan Novaković, Dragan Jovanović

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