Relationship between vitamin D status, glycemic control and chronic diabetic complications in type 2 diabetes mellitus: a retrospective study
Introduction. Vitamin D deficiency is common worldwide and has been associated with disturbances in glucose metabolism, although evidence remains inconsistent. This study evaluated serum 25(OH)D levels and their crude associations with glycemic control and chronic diabetic complications in patients with type 2 diabetes mellitus (T2DM). Methods. Th...
By Ivona Risović, Aleksandra Marković, Marijana Kovačević, Mirjana Gnjatić, Milena Brkić
Mental health consequences of the COVID-19 pandemic: a narrative review
The COVID-19 pandemic has generated a profound psychological impact across diverse populations, exposing long-standing gaps in mental health services and intensifying social inequalities. This narrative review explores the most prevalent mental health conditions associated with the pandemic including depression, anxiety, stress, and post-traumatic ...
By Danijela Radulović, Svetlana Radević, Srđan Mašić
The impact of early amplification on the social development of children with hearing loss
Introduction. Early amplification in children with hearing impairment plays a crucial role in their socioemotional and communicative development. Timely identification and intervention are essential to support better outcomes in communication, socialization, and emotional well-being. This study aimed to examine whether children who received hearing...
By Dubravka Pralica
The role of TP53, APC, and KRAS gene polymorphisms in the development of colorectal cancer
This paper discusses about colorectal cancer in correlation with certain genes. Based on the etiological factors, colorectal cancer can be stratified into familial, hereditary, and sporadic. Explorations into hereditary syndromes such as familial adenomatous polyposis and hereditary non-polyposis colorectal carcinoma have unveiled genomic alteratio...
By Igor Gavrić, Nenad Lalović, Jovan Kulić
Inhibition of neutrophil oxidative burst and NETosis by fullerene-like inorganic tungsten disulfide nanoparticles with preservation of cell viability
Introduction. Tungsten disulfide (WS₂) nanoparticles possess unique physicochemical properties, making them promising candidates for biomedical applications. While previous studies have demonstrated the in vitro biocompatibility of WS₂ in various cell lines, their effects on neutrophil function remain unexplored.Methods. Human neutrophils were isol...
By Snežana Zečević, Darinka Popović, Sara Rakočević, Vanja Mališ, Ljiljana Jojić, Marija Drakul, Dušan Mihajlović, Miodrag Čolić
Application of hyperthermic intraperitoneal chemotherapy at the University Clinical Center of Republic of Srpska
Introduction. Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is an advanced treatment modality for peritoneal malignancies, including ovarian cancer, appendix adenocarcinoma, colorectal cancer, and peritoneal metastases. This approach offers potential benefits in managing these complex conditions.Methods...
By Zoran G. Aleksić, Dragan Tomić, Velimir Škrbić, Nenad Jaćimović, Miroslav Popović, Sladibor Lakić
The role of acetylsalicylic acid in the prevention of thrombosis and its effect on the outcome of patients with COVID-19
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, was marked by a high incidence of thrombotic complications contributing to poor outcomes, particularly in hospitalized patients. Acetylsalicylic acid (ASA), known for its antiplatelet and anti-inflammatory properties, has been widely investigated for its potential role in mitigating thrombotic ...
By Verica Prodanović, Marijana Kovačević, Maksim Kovačević
The role of voice-related quality of life (V-RQOL) questionnaire in assessing quality of life in patients with vocal fold paralysis
Introduction. Vocal fold paralysis (VFP) is characterized by the immobility of one or both vocal folds, leading to impaired phonation, which significantly affects the patient’s professional and social activities. The aim of this study was to examine the importance of the Voice-related Quality of Life (V-RQOL) questionnaire in assessing the qu...
By Mirjana Gnjatić, Dalibor Vranješ, Daliborka Tadić, Zorica Novaković
Production of chemokines by mesenchymal stromal cells established from inflamed human gingiva and its modulation by lipopolysaccharide
Introduction. The role of gingiva-derived stromal cells (GMSCs) in chronic periodontitis is poorly understood. Since GMSCs modulate the inflammatory and immune responses this study aimed to investigate the production of chemokines by GMSCs established from chronic periodontitis tissue under basal conditions and after stimulation with lipopolysaccha...
By Marina Radanović, Miodrag Čolić
Using Cone Beam Computed Tomography in surgical orthodontic treatment of impacted maxillary canines - a case report
Introduction. The purpose of this case report was to present a surgical-orthodontic treatment of bilaterally impacted maxillary canines using Cone Beam Computed Tomography (CBCT). Case report. A 16-year-old girl accompanied by parents was admitted to the Specialist Center for Dentistry, Faculty of Medicine Foča, for orthodontic consultation re...
By Jelena Elez, Slavoljub Tomic, Tanja Ivanovic, Jelena Krunic