Introduction. Placental dysfunction is underlying cause in most of the intrauterine growth restriction and the pregnancy complications where the fetus does not achieve its genetically determined potential for growth. The critical process for the development of the placenta is angiogenesis. CD31 is an important endothelial adhesion protein that enab...

By Vesna Ljubojević, Sanja Jovičić, Dragica Draganović, Ljiljana Amidžić, Biljana Vatreš, Nataša Vojinović

The vascular approach is a prerequisite for performing hemodialysis, but their "weak points" are different and frequent complications. Modern guidelines recommend native arteriovenous fistula (AVF) as the first choice of vascular approach because it is characterized by the longest survival and the least complications compared to other vascular appr...

By Nenad Lalović

Pneumoconiosis of workers in brown coal mines is an occupational disease, a global public health problem and a serious disease of the lung parenchyma. If it is not prevented, it leads to irreversible changes in the lungs with complications. The disorder occurs after prolonged exposure to coal dust containing high concentration of free crystalline s...

By Biljana Čančar, Đorđe Jevtić

Genetic and environmental factors play an important role in the development of type 2 diabetes mellitus (DM2) and its complications. Diabetic nephropathy (DN) is one of the most common microangiopathic chronic complications of diabetes. Oxidative stress occurs under condition of increased production of free radicals and/or decreased activity of ant...

By Dragana Tošović Pavlović, Siniša Ristić

Introduction. Acute rhinosinusitis (ARS) encompasses a heterogeneous group of inflammatory disorders affecting nasal mucosa and paranasal sinuses. Rhinosinusitis is the most common condition in the United States. It is estimated that over 30 million people annually visit the doctor due to this condition, while every sixth adult suffers from ARS. Am...

By Ljiljana Krsmanović, Vladimir Turuntaš

There is a daily increase in the number of patients with malignant diseases, but with the advances in modern oncology research, the number of survivors treated with malignant diseases is becoming larger and larger. The survival rate after completing oncology therapy is increasing on a daily basis, so that malignant diseases belonging to the categor...

By Srđan Popović

Introduction. Whether it is a classic version of the flap or its modification, the Limberg flap is an appropriate solution for covering small and medium-sized defects, as well as for covering largesized defects where certain localizations are concerned. It represents a local, transposition flap that has proven to be a safe option. Methods. The defe...

By Zuhra Memić, Vera Sabljak, Helena Marić-Kujundžić, Bojan Kujundžić

Carcinoma of the middle ear is a rare otologic disease. The development of malignancy is most commonly associated with chronic inflammation of the middle ear, although the mechanisms of this development have not been clarified yet. The symptoms of the carcinoma are not always specific and the cancer is frequently diagnosed in its advanced stage. Ea...

By Dragoslava Đerić

Introduction. Tooth injuries are very common in children. They occur during intense physical and mental development, which complicates the clinical presentation, diagnosis, therapy and prognosis of the injured teeth. Tooth intrusion (Intrusion dentis) is an injury to the surrounding tissue characterized by axial tooth movement towards the jawbone t...

By Milica Šipovac, Jelena Galović, Ljubica Pavlović-Trifunović, Mirjana Perin, Bojan Petrović

Introduction. Thyroglossal cyst represents the most common congenital anomaly of the neck and it occurs in approximately 7% of the overall population. It develops as a consequence of obliteration failure of ductus thyreoglossus during migration of thyroid gland in embryogenesis. It is usually diagnosed during the first decade of life by clinical ex...

By Miroslav Obrenović, Siniša Kojić, Vekoslav Mitrović, Mirjana Ćuk, Borko Davidović