The COVID-19 pandemic, caused by the SARS-CoV-2 virus, was marked by a high incidence of thrombotic complications contributing to poor outcomes, particularly in hospitalized patients. Acetylsalicylic acid (ASA), known for its antiplatelet and anti-inflammatory properties, has been widely investigated for its potential role in mitigating thrombotic ...

By Verica Prodanović, Marijana Kovačević, Maksim Kovačević

Introduction: Thyroid dysfunction has been identified as one of the most common comorbidities in people with multiple sclerosis (pwMS). This study aimed to determine the prevalence of thyroid disease and vitamin D levels in patients with MS compared to the general population, and to assess the potential impact of thyroid status and vitamin D levels...

By Daliborka Tadić, Sanja Grgić, Aleksandra Dominović Kovačević, Zoran Vukojević, Gabrijela Malešević, Valentina Soldat Stankovic

Introduction. Adaptive behavior, which includes conceptual, social, and practical skills, is a key indicator of children’s daily functioning. Its assessment is particularly important in identifying intellectual disabilities, as well as in evaluating the developmental potential of children with various developmental disorders and those with ty...

By Sladjana Ćalasan, Nadica Jovanović-Simić, Bojana Drljan

Introduction. Early amplification in children with hearing impairment plays a crucial role in their socioemotional and communicative development. Timely identification and intervention are essential to support better outcomes in communication, socialization, and emotional well-being. This study aimed to examine whether children who received hearing...

By Dubravka Pralica

This paper discusses about colorectal cancer in correlation with certain genes. Based on the etiological factors, colorectal cancer can be stratified into familial, hereditary, and sporadic. Explorations into hereditary syndromes such as familial adenomatous polyposis and hereditary non-polyposis colorectal carcinoma have unveiled genomic alteratio...

By Igor Gavrić, Nenad Lalović, Jovan Kulić

Introduction. Tungsten disulfide (WS₂) nanoparticles possess unique physicochemical properties, making them promising candidates for biomedical applications. While previous studies have demonstrated the in vitro biocompatibility of WS₂ in various cell lines, their effects on neutrophil function remain unexplored.Methods. Human neutrophils were isol...

By Snežana Zečević, Darinka Popović, Sara Rakočević, Vanja Mališ, Ljiljana Jojić, Marija Drakul, Dušan Mihajlović, Miodrag Čolić

Introduction. Gastric adenocarcinoma is a major cause of global cancer mortality. The HER2 receptor plays a critical role in cell proliferation and survival and is overexpressed or amplified in a subset of gastric cancers, particularly of the intestinal type. The objective of this study was to evaluate HER2 protein expression and gene amplification...

By Mirjana Ćuk, Radoslav Gajanin, Svjetlana Kulić, Milena Vasić Milanović

Modern nursing studies the psychological characteristics of patients, manifested in both healthy and ill individuals under care, as well as those traits essential for the nurse’s professional practice, with empathy standing out in particular. Empathic sensitivity is a sign of an individual’s general level of sensitivity, and that sensit...

By Valentina Šćekić, Milena Bulatović

Metformin (dimethyl biguanide) is an oral antidiabetic agent and one of the most commonly prescribed medications in endocrinology. In addition to its primary use in treating type 2 diabetes, it has a broader range of indications and is generally considered to have a favorable safety profile. The most common side effects are gastrointestinal, includ...

By Goran Bokan, Zoran Mavija

Inguinal hernia represents a significant global health challenge, with more than 20 million operations performed annually. This paper provides a comprehensive review of contemporary practice, critically analyzing the evolution of treatment from the concept of the “gold standard” toward a personalized approach. The study integrates the l...

By Rade Miletić, Nenad Lalović, Siniša Kojić