There is a daily increase in the number of patients with malignant diseases, but with the advances in modern oncology research, the number of survivors treated with malignant diseases is becoming larger and larger. The survival rate after completing oncology therapy is increasing on a daily basis, so that malignant diseases belonging to the categor...

By Srđan Popović, Sladjana Popović, Nikolina Dukić, Olivera Čančar, Jelena Vladičić Mašić

Introduction. Hematopoiesis is the process of developing blood cells and the formed elements of blood. This dynamic process occurs postnatally in the bone marrow, while the prenatal hematopoiesis is scattered over multiple localizations. It begins in the yolk sac, in the intra-embryonic islands of hematopoiesis, and continues in the liver, spleen, ...

By Jelena Vladičić-Mašić, Ivan Nikolić, Vera Todorović, Marko Jović, Vladimir Petrović, Srđan Mašić, Nikolina Dukić, Snežana Zečević

The human epidermal growth receptor 2 (HER2, c-erb-B2) is present in 15-20% of breast cancer at the time of diagnosis. Overexpression of HER2 receptor is associated with more aggressive form of breast cancer. Trastuzumab is a human monoclonal antibody that blocks the signaling pathways of cell proliferation by binding to the HER2 receptor. Due to t...

By Dragana Jokanović, Slađana Popović, Olivera Čančar, Nikolina Dukić, Zdenka Gojković, Nenad Lalović, Jelena Vladičić Mašić, Srdjan Mašić

Uvod. Reumatoidni artritis je sistemsko, autoimunsko oboljenje koje dovodido deformacija i destrukcija zglobova, smanjujući radnu sposobnost oboljelogi značajno utičući na kvalitet života. Bolest u oko 80% bolesnika počinje postepeno,a klinički se ispolji nakon neke infekcije, tjelesne ili psihičke traume,ili porođaja. Komorbiditeti (pridružena obo...

By Ivan Radić, Verica Prodanović, Marijana Kovačević, Snežana Mališ, Nikolina Dukić

Introduction. Extramural venous invasion (EMVI) is a significant predictive factor of the prognosis for patients with colorectal carcinoma and it is directly connected with the relapse of a disease, especially with the appearance of distant metastases. Methods. The research comprises 90 patients with colorectal cancer. Representative samples of tum...

By Mirjana Ćuk, Slavica Knežević Ušaj, Ištvan Klem, Radoslav Gajanin, Danijela Batinić Škipina, Radmil Marić, Sanja Marić, Nenad Lalović, Nikolina Dukić