Quality of life after total knee arthroplasty: effects of a 21-day inpatient rehabilitation program on pain and functional recovery
Introduction. Effective rehabilitation is essential for recovery after total knee arthroplasty (TKA), yet the magnitude of benefit from intensive inpatient programs remains incompletely defined. This work aimed to evaluate the effects of a standardized 21-day inpatient rehabilitation program on pain, functional status, and health-related quali...
By Tatjana Nožica Radulović, Maja Vučković, Dragana Kožul, Stanislav Palija, Monika Jelačić, Vedran Milojević
Relationship between vitamin D status, glycemic control and chronic diabetic complications in type 2 diabetes mellitus: a retrospective study
Introduction. Vitamin D deficiency is common worldwide and has been associated with disturbances in glucose metabolism, although evidence remains inconsistent. This study evaluated serum 25(OH)D levels and their crude associations with glycemic control and chronic diabetic complications in patients with type 2 diabetes mellitus (T2DM). Methods. Th...
By Ivona Risović, Aleksandra Marković, Marijana Kovačević, Mirjana Gnjatić, Milena Brkić
Local flaps in facial skin cancer reconstruction: functional and aesthetic outcomes
Introduction. The most common malignant facial skin tumors are basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma. Surgical excision remains the gold standard of treatment, followed by reconstruction of the resulting defect. The aims of this study were to present reconstructive options for facial defects following excision of m...
By Siniša Kojić, Helena Marić Kujundžić, Bojan Kujundžić, Rade Miletić, Miroslav Obrenović, Nenad Lalović
Motivation and barriers to the use of Point-of-Care Ultrasound (POCUS) among physicians in Bosnia and Herzegovina: a dual survey study
Introduction. Point-of-care ultrasound (POCUS) is increasingly recognized as an extension of the physical examination, enhancing bedside diagnostic accuracy and real-time clinical decision-making. Although widely integrated into medical education and practice internationally, its routine implementation in Bosnia and Herzegovina remains inconsistent...
By Željka Popović, Siniša Ristić, Zagorka Blagojevic Pavlović
Myocardial perfusion imaging findings and 2-year outcomes in clinically referred asymptomatic patients with type 2 diabetes
Introduction. Type 2 diabetes mellitus is associated with an increased risk of coronary artery disease, which frequently remains clinically silent. Myocardial perfusion imaging with single-photon emission computed tomography is widely used for the detection of myocardial ischemia and risk stratification, but its prognostic value in asymptomatic dia...
By Siniša Stanković, Dragana Šobić-Šaranović, Valentina Soldat-Stanković, Vera Artiko, Zvezdana Rajkovača, Gostimir Mikač, Nataša Egeljić-Mihailović, Tanja Iličić
CDK4/6 inhibitors in HR‑positive/HER2‑negative breast cancer: a scoping review of randomised clinical trials
Introduction. Breast cancer is the most common malignancy in women and a leading cause of cancer mortality. The HR-positive/HER2-negative subtype accounts for most cases and is characterized by initial endocrine sensitivity followed by resistance. This study aimed to map and interpret randomized clinical trial evidence on the efficacy and safe...
By Sanja Stojanović Gagović, Nikolina Dukić, Jelena Vladičić Mašić, Dragana Stupar, Nemanja Kovač, Snežana Zečević
Application of hyperthermic intraperitoneal chemotherapy at the University Clinical Center of Republic of Srpska
Introduction. Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is an advanced treatment modality for peritoneal malignancies, including ovarian cancer, appendix adenocarcinoma, colorectal cancer, and peritoneal metastases. This approach offers potential benefits in managing these complex conditions.Methods...
By Zoran G. Aleksić, Dragan Tomić, Velimir Škrbić, Nenad Jaćimović, Miroslav Popović, Sladibor Lakić
Production of chemokines by mesenchymal stromal cells established from inflamed human gingiva and its modulation by lipopolysaccharide
Introduction. The role of gingiva-derived stromal cells (GMSCs) in chronic periodontitis is poorly understood. Since GMSCs modulate the inflammatory and immune responses this study aimed to investigate the production of chemokines by GMSCs established from chronic periodontitis tissue under basal conditions and after stimulation with lipopolysaccha...
By Marina Radanović, Miodrag Čolić
Using Cone Beam Computed Tomography in surgical orthodontic treatment of impacted maxillary canines - a case report
Introduction. The purpose of this case report was to present a surgical-orthodontic treatment of bilaterally impacted maxillary canines using Cone Beam Computed Tomography (CBCT). Case report. A 16-year-old girl accompanied by parents was admitted to the Specialist Center for Dentistry, Faculty of Medicine Foča, for orthodontic consultation re...
By Jelena Elez, Slavoljub Tomic, Tanja Ivanovic, Jelena Krunic
Mental health consequences of the COVID-19 pandemic: a narrative review
The COVID-19 pandemic has generated a profound psychological impact across diverse populations, exposing long-standing gaps in mental health services and intensifying social inequalities. This narrative review explores the most prevalent mental health conditions associated with the pandemic including depression, anxiety, stress, and post-traumatic ...
By Danijela Radulović, Svetlana Radević, Srđan Mašić