Positive effects of dietary approach for the treatment of hypertension
According to the World Health Organization (WHO) and the International Society for Hypertension, elevated blood pressure is defined as the blood pressure the readings of which consistently range ≥ 140 mmHg systolic and/or 90 mmHg diastolic. Having in mind the fact that hypertension is one of the leading risk factors for cardiovasluar disease, ki...
By Maja Vuković, Biljana Mijović, Miloš Maksimović, Vesna Lazić
Post-chemotherapy cognitive dysfunction in women with breast cancer
Cancer-related cognitive dysfunction is an important clinical probem that can interfere with the daily functioning, work productivity, childcare, and other responsibilities of women with a history of breast cancer. Risks of cancer-related cognitive impairment include cancer and cancer treatment, as well as patient-related vulnerabilities. There is ...
By Gorica Vuksanović, Jelena Marić, Olivera Kalajdžić, Ivana Zečević, Sandra Matovic, Siniša Ristić
The impact of TP53 and PTEN tumor suppressor genes on response to different breast cancer treatment modalities
Introduction. Breast cancer (BC) is the most frequent type of malignancy and the leading cause of cancer related death among women worldwide. BC is exceptionally heterogeneous disease and therefore distinct treatment modalities are necessary to address these differences. The aim of our study was to investigate the impact of TP53 and PTEN tumor supp...
By Nikola Tanić, Tatjana Dramićanin, Nejla Ademović, Tijana Tomić, Blagoje Murganić, Zorka Milovanović, Milica Nedeljković, Nasta Tanić
Effect of perioperative blood loss on cognitive function disorders after colon cancer surgery
Introduction. Postoperative cognitive dysfunction (POCD) is very common in patients who are treated in intensive care units or in the surgery department after surgery. This increasingly present complication complicates and calls into question the recovery of the operated patient. We assumed that POCD was associated with blood loss in patients under...
By Dalibor P. Bošković, Sanja Marić, Marko Kovačević, Bojan Golijanin
Effect of using HEART score in patients with chest pain at the emergency department of University Clinical Centre of the Republic of Srpska
Introduction. Recent data show that 1/5 of patients with chest pain in the emergency room (ER) have an acute coronary syndrome that requires admission and treatment. Current guidelines have endorsed the HEART score for admission, observation or discharge in individual patients. We aimed to assess performance of the HEART score at the Universi...
By Bojan Stanetić, Nenad Jaćimović, Šemsudin Porčić
Analysis of anatomy and configuration of the canal system of the maxillary second premolar in the population of Bosnia and Herzegovina
Introduction. Successful endodontic treatment depends upon the clinician's knowledge and ability to recognize and diagnose the presence of anatomical and morphological variations of the root and canal system. The aim of this study was to establish the number of roots and root canal configurations of the maxillary second premolar in the population o...
By Brankica Davidović, Ljiljana Bjelović, Igor Radović, Bojana Davidović, Svjetlana Janković, Smiljka Cicmil
The function of autophagy as a fundamental process of preserving cell homeostasis
Autophagy is a dynamic process, conserved in all eukaryotes. It is responsible for the degradation of cytoplasmic content. Autophagy is crucial in cell survival and cell death. It plays a significant role in the cell response to stress, nutrient deficiencies, embryonic development, tumor suppression, response to pathogens and aging. The process of ...
By Nikolina Elez-Burnjaković, Lejla Pojskić, Sanin Haverić, Ajla Smajlović
The role of glutathione transferase polymorphisms in the development of diabetic nephropathy
Genetic and environmental factors play an important role in the development of type 2 diabetes mellitus (DM2) and its complications. Diabetic nephropathy (DN) is one of the most common microangiopathic chronic complications of diabetes. Oxidative stress occurs under condition of increased production of free radicals and/or decreased activity of ant...
By Dragana Tošović Pavlović, Siniša Ristić
Seroprevalence of SARS-CoV-2 virus infection in employees in the health insurance sector
Introduction. Serological testing for SARS-CoV-2 virus infection is a valuable method of estimating the extent of COVID-19 disease prevalence. The study aims to assess the seroprevalence of SARS-CoV-2 virus infection in a specific group of respondents employed in the health insurance sector, to determine the ratio of symptomatic and asymptomatic ca...
By Dragan Spaić, Anđela Mandić, Biljana Mijović, Srdjan Mašić, Dejan Bokonjić, Dragana Puhalo Sladoje
The importance of physical activity in diabetes
Introduction. Obesity is becoming a global urgent issue that is considered a health problem in developed and developing countries. Obesity is a major risk factor for many non-communicable diseases such as cardiovascular diseases, type 2 diabetes mellitus (DM2), hypertension, coronary heart disease, or certain types of cancer. Physical activity is c...
By Miloš Purković, Danka Vukašinović, Una Radak