Production of chemokines by mesenchymal stromal cells established from inflamed human gingiva and its modulation by lipopolysaccharide
Introduction. The role of gingiva-derived stromal cells (GMSCs) in chronic periodontitis is poorly understood. Since GMSCs modulate the inflammatory and immune responses this study aimed to investigate the production of chemokines by GMSCs established from chronic periodontitis tissue under basal conditions and after stimulation with lipopolysaccha...
By Marina Radanović, Miodrag Čolić
Using Cone Beam Computed Tomography in surgical orthodontic treatment of impacted maxillary canines - a case report
Introduction. The purpose of this case report was to present a surgical-orthodontic treatment of bilaterally impacted maxillary canines using Cone Beam Computed Tomography (CBCT). Case report. A 16-year-old girl accompanied by parents was admitted to the Specialist Center for Dentistry, Faculty of Medicine Foča, for orthodontic consultation re...
By Jelena Elez, Slavoljub Tomic, Tanja Ivanovic, Jelena Krunic
Mental health consequences of the COVID-19 pandemic: a narrative review
The COVID-19 pandemic has generated a profound psychological impact across diverse populations, exposing long-standing gaps in mental health services and intensifying social inequalities. This narrative review explores the most prevalent mental health conditions associated with the pandemic including depression, anxiety, stress, and post-traumatic ...
By Danijela Radulović, Svetlana Radević, Srđan Mašić
The impact of early amplification on the social development of children with hearing loss
Introduction. Early amplification in children with hearing impairment plays a crucial role in their socioemotional and communicative development. Timely identification and intervention are essential to support better outcomes in communication, socialization, and emotional well-being. This study aimed to examine whether children who received hearing...
By Dubravka Pralica
The role of TP53, APC, and KRAS gene polymorphisms in the development of colorectal cancer
This paper discusses about colorectal cancer in correlation with certain genes. Based on the etiological factors, colorectal cancer can be stratified into familial, hereditary, and sporadic. Explorations into hereditary syndromes such as familial adenomatous polyposis and hereditary non-polyposis colorectal carcinoma have unveiled genomic alteratio...
By Igor Gavrić, Nenad Lalović, Jovan Kulić
Inhibition of neutrophil oxidative burst and NETosis by fullerene-like inorganic tungsten disulfide nanoparticles with preservation of cell viability
Introduction. Tungsten disulfide (WS₂) nanoparticles possess unique physicochemical properties, making them promising candidates for biomedical applications. While previous studies have demonstrated the in vitro biocompatibility of WS₂ in various cell lines, their effects on neutrophil function remain unexplored.Methods. Human neutrophils were isol...
By Snežana Zečević, Darinka Popović, Sara Rakočević, Vanja Mališ, Ljiljana Jojić, Marija Drakul, Dušan Mihajlović, Miodrag Čolić
The prognostic significance of HER2 in gastric adenocarcinoma
Introduction. Gastric adenocarcinoma is a major cause of global cancer mortality. The HER2 receptor plays a critical role in cell proliferation and survival and is overexpressed or amplified in a subset of gastric cancers, particularly of the intestinal type. The objective of this study was to evaluate HER2 protein expression and gene amplification...
By Mirjana Ćuk, Radoslav Gajanin, Svjetlana Kulić, Milena Vasić Milanović
A culture of empathy in nursing clinical practice
Modern nursing studies the psychological characteristics of patients, manifested in both healthy and ill individuals under care, as well as those traits essential for the nurse’s professional practice, with empathy standing out in particular. Empathic sensitivity is a sign of an individual’s general level of sensitivity, and that sensit...
By Valentina Šćekić, Milena Bulatović
Evolution of hospitalized COVID-19 cases with emphasis on the first pandemic year: experience from the University Clinical Center of Republic of Srpska
Introduction. Infection caused by the novel coronavirus (SARSCoV-2) emerged in 2019 in China and rapidly spread worldwide. This highly contagious virus is transmitted primarily through respiratory droplets and may lead to Severe Acute Respiratory Syndrome (SARS). The World Health Organization (WHO) declared Coronavirus Disease 2019 (COVID-19) a glo...
By Nataša Janjić, Goran Bokan, Uroš Kalajdžić, Antonija Verhaz, Slavica Zeljković, Zoran Mavija
Knowledge and competence of nurses and prevalence of pressure ulcers in stroke patients
Introduction. Pressure ulcers are frequent complications among immobile neurological patients, particularly those with stroke. Nursing knowledge and consistent implementation of preventive measures play a crucial role in reducing their occurrence. The aims of this study are to assess nurses’ knowledge, attitudes and self-reported competence i...
By Verica Petrovic, Anes Budimlić, Kosana Stanetić, Suzana Savić, Gordana Tešanović