The human epidermal growth receptor 2 (HER2, c-erb-B2) is present in 15-20% of breast cancer at the time of diagnosis. Overexpression of HER2 receptor is associated with more aggressive form of breast cancer. Trastuzumab is a human monoclonal antibody that blocks the signaling pathways of cell proliferation by binding to the HER2 receptor. Due to t...

By Dragana Jokanović, Slađana Popović, Olivera Čančar, Nikolina Dukić, Zdenka Gojković, Nenad Lalović, Jelena Vladičić Mašić, Srdjan Mašić

Introduction. Aggressive behavior is defined as the behavior of such intensity, frequency and duration that it seriously threatens the physical safety of a person/persons or the one which seriously limits their social functioning. The aim of the paper is to determine the intensity and forms of aggression in institutionalized women with intellectual...

By Bojana Mastilo, Bojana Vuković, Stevan Šeatović, Sladjana Ćalasan

Progress in diagnosis and treatment has led to a significant improvement in the fate of children born with tetralogy of Fallot, with the perioperative mortality of 2-3% and a 30-year survival rate of 90%. However, the majority of these patients have residual postoperative morphological and hemodynamic disorders, as well as heart rhythm disorders, p...

By Biljana Milinković, Dejan Bokonjić, Verica Prodanović

Introduction. The optic nerve is supplied by the arterial branches of the supericial pial plexus and direct intraneural branches. The aim of the study was to study the morphological characteristics (origin, number of arteries, calibers, and branching pattern) of perioptic arterial vascularization and intraoptic vascular network of the extracranial ...

By Radmila Balaban-Đurević, Samra Hajrović, Vanja Pljevaljčić, Valvita Reçi, Stefan Kulić, Milan Milisavljević, Siniša Šolaja

Introduction. Larynx carcinoma is one of the most common malignant tumors of the upper aerodigestive tract that causes the change in normal anatomical relationships in the neck, which leads to communication and social interaction disorders. The aim of the paper is to examine the impact of education on the quality of life of laryngectomized patients...

By Mila Bunijevac, Mirjana Petrović-Lazić, Siniša Maksimović

Hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) are the main bloodborne pathogens and are of considerable interest for the dental team. In dentist's surgery, HBV, HCV and HIV infections can be transmitted via direct contact with blood and saliva containing blood, or via indirect contact with contaminated den...

By Jovana Hrisa-Samardžija, Marina Milinković, Biljana Mijović

Introduction. Depressive disorder is common in patients with the diagnosis of alcoholism. Comorbidity of depression and alcoholism significantly worsens the clinical status of patients and represents a major therapeutic challenge. The aim of the study was to investigate the effect of the antidepressant drug venlafaxine on the length of QT interval ...

By Sanja Vukadinović-Stojanović, Zlatan Stojanović

Introduction.Voice is the result of vocal cord vibrations and resonance effects of the vocal tract, therefore, the instrumental monitoring of the vibrations themselves is one of the essential aspects of objective instrumental assessment of voice. Inadequate height and volume, as well as increased nasality, represent the basic characteristics of voi...

By Slađana Ćalasan, Nadica Jovanović-Simić, Snežana Babac, Mirjana Petrović-Lazić

Introduction. The automatic suspension of the insulin pump and discontinuation of insulin delivery in case of hypoglycemia is one of the features of Veo insulin pump when it is connected with the sensor used for continuous monitoring of glycemia (CGM). This type of therapy is currently considered to be the best one for achieving a good metabolic co...

By Vesna Miljković, Gordana Bukara Radujković

Introduction. The aim of the study is to examine the frequence of both early and later postoperative complications of arteriovenous fistula (AVF), as well as to determine the factors associated with the patency loss of AVF. Methods. The examination included 250 patients underwent native lower-arm AVF for hemodialysis createion, after which they had...

By Nebojša Tasić, Nikola Gavrić, Zlatko Maksimović, Siniša Maksimović