Introduction. Chronic rhinosinusitis with sinonasal polyposis is a chronic inflammatory process of the mucous membranes of the nasal and paranasal sinuses, clinically manifested by the appearance of polyps in the nasal cavity. The presence of polyps in the nose and sinuses is the cause of the characteristic symptoms that affect the quality of life ...

By Aleksandra Aleksić, Zorica Novaković, Nataša Guzina-Golac, Vojin Vojnović, Željko Markić, Siniša Šolaja

Introduction. Intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents has revolutionized the management of age-related macular degeneration (AMD), diabetic macular edema (DME), macular edema in retinal vein occlusions (RVO), and other retinal diseases accompanied by neovascular and macular edema. The aim of the study is to s...

By Dijana Risimić, Jelena Karadžić, Miroslav Jeremić, Nada Avram

Introduction. Burnout syndrome is a common problem among healthcare workers. The aim of the study was to investigate the level of stress, components of burnout syndrome and the most common causes of workplace stress among the physicians working in the Primary Health Care Center Banja Luka, after which the obtained results concerning family physicia...

By Brankica Marković, Kosana Stanetić, Verica Petrović, Bojan Stanetić

Introduction. The presence of anxiety and depressive disorders in at least one partner adversely affects the quality of partnership relations. The aim of the study is to determine the degree of partner relationship satisfaction in relation to the existence of anxiety and depressive disorders. Methods. The sample included 107 subjects divided into t...

By Mira Spremo, Nada Vaselić

Introduction. Secondary failure to treatment with oral antidiabetic agents is defined as the absence of a favorable reaction to the oral therapy which had proved effective in the previous course of the treatment. The aim of the study is to investigate the residual effects of the short-term combination therapy with insulin on glycoregulation and ins...

By Aleksandra Grbić, Gabrijela Malešević, Slavko Grbić, Milorad Grujičić, Vesna Jelača

Introduction. Aging is a biological process leading to the decrease in functional ability which is defined as an ability to perform activities of daily living in a secure, independent and effective way. The aim of the study was to examine the functional ability of men aged ≥ 65 years as well as to determine the differences in functional ability ...

By Ilija Stijepić, Tamara Popović, Dragana Sredić-Cartes

The human epidermal growth receptor 2 (HER2, c-erb-B2) is present in 15-20% of breast cancer at the time of diagnosis. Overexpression of HER2 receptor is associated with more aggressive form of breast cancer. Trastuzumab is a human monoclonal antibody that blocks the signaling pathways of cell proliferation by binding to the HER2 receptor. Due to t...

By Dragana Jokanović, Slađana Popović, Olivera Čančar, Nikolina Dukić, Zdenka Gojković, Nenad Lalović, Jelena Vladičić Mašić, Srdjan Mašić

Introduction. Peripheral arterial disease (PAD) is a progressive, occlusive and atherosclerotic vascular disease and patients with type 2 diabetes mellitus (DM) are at increased risk of developing this disease. The aim of the study was to determine the frequency of PAD in patients with type 2 DM by measuring the ankle-brachial index (ABI) in the fa...

By Biljana Lakić, Saša Turajlić, Verica Petrović

Surgical treatment of locally advanced gastrointestinal cancer alone does not exhibit satisfactory local disease control and survival rate. The advantage of using radio and chemotherapy at this stage is to reduce the likelihood of developing local recurrence with an extension of survival time, while the disadvantages are the increase in postoperati...

By Ljiljana Vasić

Introduction. The optic nerve is supplied by the arterial branches of the supericial pial plexus and direct intraneural branches. The aim of the study was to study the morphological characteristics (origin, number of arteries, calibers, and branching pattern) of perioptic arterial vascularization and intraoptic vascular network of the extracranial ...

By Radmila Balaban-Đurević, Samra Hajrović, Vanja Pljevaljčić, Valvita Reçi, Stefan Kulić, Milan Milisavljević, Siniša Šolaja