Cardio-oncology: New challenge in clinical practice
There is a daily increase in the number of patients with malignant diseases, but with the advances in modern oncology research, the number of survivors treated with malignant diseases is becoming larger and larger. The survival rate after completing oncology therapy is increasing on a daily basis, so that malignant diseases belonging to the categor...
By Srđan Popović, Sladjana Popović, Nikolina Dukić, Olivera Čančar, Jelena Vladičić Mašić
Neoadjuvant therapy for HER2-positive breast cancer
The human epidermal growth receptor 2 (HER2, c-erb-B2) is present in 15-20% of breast cancer at the time of diagnosis. Overexpression of HER2 receptor is associated with more aggressive form of breast cancer. Trastuzumab is a human monoclonal antibody that blocks the signaling pathways of cell proliferation by binding to the HER2 receptor. Due to t...
By Dragana Jokanović, Slađana Popović, Olivera Čančar, Nikolina Dukić, Zdenka Gojković, Nenad Lalović, Jelena Vladičić Mašić, Srdjan Mašić
Diabetic nephropathy in type 2 diabetes: The frequency and risk factors
Introduction. The aim of the study was to determine the frequency and risk factors for diabetic nephropathy (DN) in patients with type 2 diabetes as well as the factors related to kidney function decrease over a three-year period. Methods. The study involved 81 patients with type 2 diabetes, initially classified into two groups: the first group was...
By Maksim Kovačević, Nenad Petković, Marijana Kovačević, Snežana Mališ, Verica Prodanović, Olivera Čančar, Siniša Ristić, Ljubica Djukanović
Oxidative stress and other risk factors associated with diabetic nephropathy in type 2 diabetes mellitus
Introduction. The aim of the study was to examine whether biomarkers of oxidative stress and antioxidant enzyme activities are among other risk factors for diabetic nephropathy (DN). Methods. The study involved 70 patients with type 2 diabetes (37 males, aged 41 to 81 years) allocated to two groups: one of 32 patients with DN and the other of 38 pa...
By Snežana Mališ, Ana Savić-Radojević, Marijana Kovačević, Dragana Pavlović, Olivera Čančar, Ljubica Djukanović
Porođaj nakon carskog reza i perinatalni ishod novorođenčadi
Uvod. Dugo vremena je u akušerstvu važio čuveni diktum Edwarda Craginaiz 1916. godine: ”Jednom carski rez, uvijek carski rez”. Vremenom, rukovodećise postupcima iz prošlosti i porastom broja patoloških trudnoća sa jednestrane, kao i uticajem medija i zahtjevima pacijenata sa druge strane, procenatporođaja zavr&scaro...
By Radenko Ivanović, Radoslavka Lečić, Vladimir Čančar, Olivera Čančar, Dragana Puhalo Sladoje