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Vitamin D and atherosclerosis

By
Vesna Lazić ,
Vesna Lazić

Regional Center Zvornik, Public Health Institute of the Republic of Srpska ,Banja Luka ,Bosnia and Herzegovina

Biljana Mijović ,
Biljana Mijović

Faculty of Medicine Foca, University of East Sarajevo ,Lukavica ,Bosnia and Herzegovina

Miloš Maksimović ,
Miloš Maksimović

Faculty of Medicine, Belgrade, Serbia, University of Belgrade ,Belgrade ,Serbia

Olivera Rašević ,
Olivera Rašević

Faculty of Medicine, Foca, University of East Sarajevo ,Lukavica ,Bosnia and Herzegovina

Maida Mulić ,
Maida Mulić

University Clinical Center Tuzla ,Tuzla ,Bosnia and Herzegovina

Maja Vuković ,
Maja Vuković

Faculty of Medicine, Foca, The Republic of Srpska, Bosnia and Herzegovina, University of East Sarajevo ,Lukavica ,Bosnia and Herzegovina

Abstract

Cardiovascular diseases rank first on the mortality list globally or 31%. The basic measure of prevention in accordance with the recommendations of the World Health Organization is a change in risk lifestyle in terms of diet, physical activity, tobacco and alcohol consumption. Vitamin D was previously recognized as a regulator of calcium and phosphorus ratio, bone remodeling or the main controller of skeletal pathophysiology. However, vitamin D enjoys great interest in clinical and epidemiological research in terms of its possible impact on reducing the risk of cardiovascular diseases. Among other things, vitamin D deficiency is associated with an increased risk of endothelial dysfunction. Although the deficiency has been identified as a risk marker for cardiovascular diseases, the mechanism of action of vitamin D on the path from endothelial dysfunction to cardiovascular diseases has not been fully revealed. The findings in this segment of activity of vitamin D would be significant in terms of reducing morbidity and mortality from cardiovascular diseases.

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