The impact of TP53 and PTEN tumor suppressor genes on response to different breast cancer treatment modalities
Introduction. Breast cancer (BC) is the most frequent type of malignancy and the leading cause of cancer related death among women worldwide. BC is exceptionally heterogeneous disease and therefore distinct treatment modalities are necessary to address these differences. The aim of our study was to investigate the impact of TP53 and PTEN tumor supp...
By Nikola Tanić, Tatjana Dramićanin, Nejla Ademović, Tijana Tomić, Blagoje Murganić, Zorka Milovanović, Milica Nedeljković, Nasta Tanić
Immunohistochemical markers: Carcinoembryonic antigen, p53, Ki-67, and proliferating cell nuclear antigen as prognostic factors for colorectal cancer
Introduction. There has been a progressive increase in the frequency of colorectal carcinoma for the last twenty years. In order for a doctor to estimate the life expectancy and/or the treatment of these patients, oncology makes use of prognostic and predictive factors. They are divided into: clinicosurgical, pathohistological and immunohistochemic...
By Siniša Maksimović, Branislava Jakovljević, Zdenka Gojković, Zlatko Maksimović
Conjunctival dysplasia in pterygium – case report
The study concerns a 65-year-old female patient with pterygium of right eye and histologically verified conjunctival intraepithelial neoplasia. The lesion was diagnosed as pterygium and treated surgically. Histological examination of the excised material found the presence of conjunctival intraepithelial neoplasia. The significance of this case rep...
By Ljilja Amidžić