Introduction. Epulis is a change in gingival tissue that occurs under the influence of chronic irritation. Histologically, there are several different types of epulis. Fibrous epulis is benign tumor of gingiva that most often occurs in interdental papilla area as a result of local irritation (inadequate restorative fillings, carious teeth, subgingi...

By Marina Radanović, Slavoljub Tomić, Tanja Ivanović, Ana Cicmil, Jovana Hrisa Samardžija, Srdjan Radanović, Jelena Lečić

According to the World Health Organization (WHO) and the International Society for Hypertension, elevated blood pressure is defined as the blood pressure the readings of which consistently range ≥ 140 mmHg systolic and/or 90 mmHg diastolic. Having in mind the fact that hypertension is one of the leading risk factors for cardiovasluar disease, ki...

By Maja Vuković, Biljana Mijović, Miloš Maksimović, Vesna Lazić

The vascular approach is a prerequisite for performing hemodialysis, but their "weak points" are different and frequent complications. Modern guidelines recommend native arteriovenous fistula (AVF) as the first choice of vascular approach because it is characterized by the longest survival and the least complications compared to other vascular appr...

By Nenad Lalović

Introduction. Patients affected with Allan-Herndon-Dudley syndrome (AHDS) have a deficiency of monocarboxylate transporter 8 (MCT8), a protein primarily responsible for the transport of triiodothyronine (T3) into the brain. This X-linked disorder affects almost exclusively males with clinical presentation encompassing developmental delay, axial hyp...

By Adrijan Sarajlija, Slađana Todorović, Biljana Alimpić, Maja Čehić

Introduction. Stroke is one of the leading causes of morbidity and mortality worldwide. The relationship between metabolic syndrome (MetS) and homocysteinemia (Hcy) as risk factors for ischemic stroke (IS) is not completely clear. The aim of the study was to determine the frequency of MetS, serum level of Hcy and the frequency of hyperhomocysteinem...

By Milorad Vujnić, Alma Prtina, Tatjana Milivojac

Introduction. Peripheral arterial disease (PAD) is a progressive, occlusive and atherosclerotic vascular disease and patients with type 2 diabetes mellitus (DM) are at increased risk of developing this disease. The aim of the study was to determine the frequency of PAD in patients with type 2 DM by measuring the ankle-brachial index (ABI) in the fa...

By Biljana Lakić, Saša Turajlić, Verica Petrović

The human epidermal growth receptor 2 (HER2, c-erb-B2) is present in 15-20% of breast cancer at the time of diagnosis. Overexpression of HER2 receptor is associated with more aggressive form of breast cancer. Trastuzumab is a human monoclonal antibody that blocks the signaling pathways of cell proliferation by binding to the HER2 receptor. Due to t...

By Dragana Jokanović, Slađana Popović, Olivera Čančar

Carcinoma of the middle ear is a rare otologic disease. The development of malignancy is most commonly associated with chronic inflammation of the middle ear, although the mechanisms of this development have not been clarified yet. The symptoms of the carcinoma are not always specific and the cancer is frequently diagnosed in its advanced stage. Ea...

By Dragoslava Đerić

Hydrocephalus is a hydrodynamic disorder of the cerebrospinal cortex causing an enlargement of the ventricular system and increased pressure around the brain. Hydrocephalus can be divided into congenital and acquired, and, based on occurrence mechanism, into communicative (non-obstructive) and non-communicative (obstructive which can be congenital ...

By Vjeran Saratlić, Vesna Ivanišević

Introduction. Celiac disease is an autoimmune disease resulting from an inadequate immune response to gluten in genetically predisposed individuals as a result of consuming gluten and other related proteins present in wheat, rye, barley and oats. The only cure for this specific disease is a strict, carefully controlled and lifelong gluten-free diet...

By Biljana Stojanović-Jovanović, Stevan Jovanović, Biljana Vuletić