Genetic and environmental factors play an important role in the development of type 2 diabetes mellitus (DM2) and its complications. Diabetic nephropathy (DN) is one of the most common microangiopathic chronic complications of diabetes. Oxidative stress occurs under condition of increased production of free radicals and/or decreased activity of ant...

By Dragana Tošović Pavlović, Siniša Ristić

Introduction. The aim of the study was to determine the frequency and risk factors for diabetic nephropathy (DN) in patients with type 2 diabetes as well as the factors related to kidney function decrease over a three-year period. Methods. The study involved 81 patients with type 2 diabetes, initially classified into two groups: the first group was...

By Maksim Kovačević, Nenad Petković

Introduction. The aim of the study was to examine whether biomarkers of oxidative stress and antioxidant enzyme activities are among other risk factors for diabetic nephropathy (DN). Methods. The study involved 70 patients with type 2 diabetes (37 males, aged 41 to 81 years) allocated to two groups: one of 32 patients with DN and the other of 38 pa...

By Snežana Mališ, Ana Savić-Radojević, Marijana Kovačević, Dragana Pavlović

Introduction. Apart from diabetic nephropathy diabetic patients may experience a nondiabetic kidney disease and the kidney biopsy is the best way to diagnose it. The aim of the study is to show the frequency und type of nondiabetic kidney disease diagnosed by kidney biopsy in diabetic patients.Methods. We presented the results of renal biopsy in di...

By Gordana Basta Jovanović, Aleksandra Salapura, Dragan Vojvodić