Introduction. The World Health Organization (WHO) defines burnout syndrome as a condition caused by chronic stress at work, which may be associated with the onset and worsening of psychosomatic illnesses and the quality of life of sufferers. The aim of the work was to determine the prevalence of burnout syndrome in the population of people with lea...

By Vesna Krstović Spremo, Sanja Marić, Ljiljana Kulić

Autophagy is a dynamic process, conserved in all eukaryotes. It is responsible for the degradation of cytoplasmic content. Autophagy is crucial in cell survival and cell death. It plays a significant role in the cell response to stress, nutrient deficiencies, embryonic development, tumor suppression, response to pathogens and aging. The process of ...

By Nikolina Elez-Burnjaković, Lejla Pojskić, Sanin Haverić, Ajla Smajlović

Genetic and environmental factors play an important role in the development of type 2 diabetes mellitus (DM2) and its complications. Diabetic nephropathy (DN) is one of the most common microangiopathic chronic complications of diabetes. Oxidative stress occurs under condition of increased production of free radicals and/or decreased activity of ant...

By Dragana Tošović Pavlović, Siniša Ristić

Introduction. Obesity is becoming a global urgent issue that is considered a health problem in developed and developing countries. Obesity is a major risk factor for many non-communicable diseases such as cardiovascular diseases, type 2 diabetes mellitus (DM2), hypertension, coronary heart disease, or certain types of cancer. Physical activity is c...

By Miloš Purković, Danka Vukašinović, Una Radak

Atherosclerosis is the leading cause of cardiovascular disease (CVD) worldwide. Recently, mortality and morbidity from CVD have shown a trend in its occurrence in earlier years, while these diseases have been associated with older age until recently. In developed countries, mortality from diseases caused by atherosclerosis has decreased over the la...

By Vesna Lazić, Biljana Mijović, Miloš Maksimović

Chronic non-communicable diseases are diseases that arise as a response of the human body to a number of factors, the most important of which are ecological and socio-economic factors. According to the World Health Organization, their classification is based on mortality and morbidity statistics. The top four leading causes of death are as follows:...

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Introduction. Peripheral arterial disease (PAD) is a progressive, occlusive and atherosclerotic vascular disease and patients with type 2 diabetes mellitus (DM) are at increased risk of developing this disease. The aim of the study was to determine the frequency of PAD in patients with type 2 DM by measuring the ankle-brachial index (ABI) in the fa...

By Biljana Lakić, Saša Turajlić, Verica Petrović

Introduction. Secondary failure to treatment with oral antidiabetic agents is defined as the absence of a favorable reaction to the oral therapy which had proved effective in the previous course of the treatment. The aim of the study is to investigate the residual effects of the short-term combination therapy with insulin on glycoregulation and ins...

By Aleksandra Grbić, Gabrijela Malešević, Slavko Grbić, Milorad Grujičić, Vesna Jelača

Introduction. The aim of the study was to determine the frequency and risk factors for diabetic nephropathy (DN) in patients with type 2 diabetes as well as the factors related to kidney function decrease over a three-year period. Methods. The study involved 81 patients with type 2 diabetes, initially classified into two groups: the first group was...

By Maksim Kovačević, Nenad Petković

Introduction. Chronic kidney diseases are global health problem and thus close attention is devoted to their prevention and early detection. The aim of the study was to assess the prevalence of chronic kidney disease biomarkers in three groups at risk. Methods. The study included 77 persons divided into three groups: (1) 31 patients with hypertensi...

By Svetlana Krsmanović