Introduction. Multiparametric magnetic resonance mammography (mMRM) has an important role in detection, evaluation and follow-up of breast lesions. The aim of this study was to explore whether imaging parameters, in particular ADC, can be used as a biomarker of cell proliferation in breast cancer. Methods. This cohort-study included 67 lesions in 5...

By Jelena Marić, Jasmina Boban, Tatjana Ivković-Kapicl, Dragana Djilas, Viktorija Vučaj-Ćirilović, Dragana Bogdanović-Stojanović

Cancer-related cognitive dysfunction is an important clinical probem that can interfere with the daily functioning, work productivity, childcare, and other responsibilities of women with a history of breast cancer. Risks of cancer-related cognitive impairment include cancer and cancer treatment, as well as patient-related vulnerabilities. There is ...

By Gorica Vuksanović, Jelena Marić, Olivera Kalajdžić, Ivana Zečević, Sandra Matovic, Siniša Ristić

Introduction. Breast cancer (BC) is the most frequent type of malignancy and the leading cause of cancer related death among women worldwide. BC is exceptionally heterogeneous disease and therefore distinct treatment modalities are necessary to address these differences. The aim of our study was to investigate the impact of TP53 and PTEN tumor supp...

By Nikola Tanić, Tatjana Dramićanin, Nejla Ademović, Tijana Tomić, Blagoje Murganić, Zorka Milovanović, Milica Nedeljković, Nasta Tanić

The human epidermal growth receptor 2 (HER2, c-erb-B2) is present in 15-20% of breast cancer at the time of diagnosis. Overexpression of HER2 receptor is associated with more aggressive form of breast cancer. Trastuzumab is a human monoclonal antibody that blocks the signaling pathways of cell proliferation by binding to the HER2 receptor. Due to t...

By Dragana Jokanović, Slađana Popović, Olivera Čančar