Autophagy is a dynamic process, conserved in all eukaryotes. It is responsible for the degradation of cytoplasmic content. Autophagy is crucial in cell survival and cell death. It plays a significant role in the cell response to stress, nutrient deficiencies, embryonic development, tumor suppression, response to pathogens and aging. The process of ...

By Nikolina Elez-Burnjaković, Lejla Pojskić, Sanin Haverić, Ajla Smajlović

Introduction. Tinnitus is a perception of a sound in the ears in the absence of acoustic stimulation whose pathophysiological mechanisms have not been evaluated yet. Approximately, 1-2% of people report distress which can negatively affect their daily performance. Our study aimed to assess the incidence of anxiety in patients with tinnitus. Methods...

By Nenad Arsović, Zoran Dudvarski, Gabrijela Šolaja, Ljiljana Krsmanović, Siniša Šolaja, Bojan Joksimović

Introduction. The inflammatory mediators play a central role in the pathogenesis of the inflammatory process of the middle ear and cholesteatoma from the aspect of initiating and maintaining the inflammatory response to infection and lesion. The aim of the study was to examine if the presence of acquired cholesteatoma could predict pathomorphologic...

By Predrag Špirić, Mirjana Gnjatić, Dalibor Vranješ

In industry and the public sector quality has become the important management challenge of the 21st century. Although quality should be self-understanding in healthcare the reality shows another picture. There are nowadays international standards and models of quality excellence which make the introduction and control of quality management even in ...

By Hans-Günther Sonntag

Pneumoconiosis of workers in brown coal mines is an occupational disease, a global public health problem and a serious disease of the lung parenchyma. If it is not prevented, it leads to irreversible changes in the lungs with complications. The disorder occurs after prolonged exposure to coal dust containing high concentration of free crystalline s...

By Biljana Čančar, Đorđe Jevtić

Introduction. Stroke is one of the leading causes of morbidity and mortality worldwide. The relationship between metabolic syndrome (MetS) and homocysteinemia (Hcy) as risk factors for ischemic stroke (IS) is not completely clear. The aim of the study was to determine the frequency of MetS, serum level of Hcy and the frequency of hyperhomocysteinem...

By Milorad Vujnić, Alma Prtina, Tatjana Milivojac

Introduction. Alcoholic liver cirrhosis is an advanced stage of progressive liver failure with an often adverse outcome. Numerous scoring systems are used to predict outcomes. The results of MELD Score (Model For End-Stage Liver Disease) and CLIF Consortium Acute Decompensation score (CLIF-C ADs) were used in this paper to determine which one is mo...

By Goran Bokan, Zoran Mavija

Atherosclerosis is the leading cause of cardiovascular disease (CVD) worldwide. Recently, mortality and morbidity from CVD have shown a trend in its occurrence in earlier years, while these diseases have been associated with older age until recently. In developed countries, mortality from diseases caused by atherosclerosis has decreased over the la...

By Vesna Lazić, Biljana Mijović, Miloš Maksimović

Chronic non-communicable diseases are diseases that arise as a response of the human body to a number of factors, the most important of which are ecological and socio-economic factors. According to the World Health Organization, their classification is based on mortality and morbidity statistics. The top four leading causes of death are as follows:...

By Vesna Lazić, Biljana Mijović, Miloš Maksimović

Introduction. The amniotic membrane is used in transplant surgery, ophthalmology and dermatology. Various methods have been developed to preserve amniotic membrane: hypothermic storage, cryopreservation, lyophilization. Transplantation of fresh amniotic membrane showed low inflammatory response. The efficient antibiotic solutions are carefully chos...

By Vesna Ljubojević, Sanja Jovičić, Milka Mavija, Zoran Vujković