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There is a daily increase in the number of patients with malignant diseases, but with the advances in modern oncology research, the number of survivors treated with malignant diseases is becoming larger and larger. The survival rate after completing oncology therapy is increasing on a daily basis, so that malignant diseases belonging to the categor...

By SLAĐANA POPOVIĆ, SRĐAN POPOVIĆ, NIKOLINA DUKIĆ, JELENA VLADIČIĆ-MAŠIĆ, OLIVERA ČANČAR

The human epidermal growth receptor 2 (HER2, c-erb-B2) is present in 15-20% of breast cancer at the time of diagnosis. Overexpression of HER2 receptor is associated with more aggressive form of breast cancer. Trastuzumab is a human monoclonal antibody that blocks the signaling pathways of cell proliferation by binding to the HER2 receptor. Due to t...

By NIKOLINA DUKIĆ, ZDENKA GOJKOVIĆ, NENAD LALOVIĆ, JELENA VLADIČIĆ-MAŠIĆ, DRAGANA JOKANOVIĆ, SRĐAN MAŠIĆ, SLAĐANA POPOVIĆ, OLIVERA ČANČAR

Introduction. The aim of the study was to determine the frequency and risk factors for diabetic nephropathy (DN) in patients with type 2 diabetes as well as the factors related to kidney function decrease over a three-year period. Methods. The study involved 81 patients with type 2 diabetes, initially classified into two groups: the first group was...

By MARIJANA KOVAČEVIĆ, SNEŽANA MALIŠ, MAKSIM KOVAČEVIĆ, VERICA PRODANOVIĆ, OLIVERA ČANČAR, SINIŠA RISTIĆ, NENAD PETKOVIĆ, LJUBICA ĐUKANOVIĆ

Introduction. The aim of the study was to examine whether biomarkers of oxidative stress and antioxidant enzyme activities are among other risk factors for diabetic nephropathy (DN). Methods. The study involved 70 patients with type 2 diabetes (37 males, aged 41 to 81 years) allocated to two groups: one of 32 patients with DN and the other of 38 pa...

By SNEŽANA MALIŠ, ANA SAVIĆ-RADOJEVIĆ, MARIJANA KOVAČEVIĆ, OLIVERA ČANČAR, DRAGANA PAVLOVIĆ, LJUBICA ĐUKANOVIĆ

Uvod. Dugo vremena je u akušerstvu važio čuveni diktum Edwarda Craginaiz 1916. godine: ”Jednom carski rez, uvijek carski rez”. Vremenom, rukovodećise postupcima iz prošlosti i porastom broja patoloških trudnoća sa jednestrane, kao i uticajem medija i zahtjevima pacijenata sa druge strane, procenatporođaja zavr&scaro...

By VLADIMIR ČANČAR, RADENKO IVANOVIĆ, RADOSLAVKA LEČIĆ, OLIVERA ČANČAR, DRAGANA PUHALO SLADOJE