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The human epidermal growth receptor 2 (HER2, c-erb-B2) is present in 15-20% of breast cancer at the time of diagnosis. Overexpression of HER2 receptor is associated with more aggressive form of breast cancer. Trastuzumab is a human monoclonal antibody that blocks the signaling pathways of cell proliferation by binding to the HER2 receptor. Due to t...

By NIKOLINA DUKIĆ, ZDENKA GOJKOVIĆ, NENAD LALOVIĆ, JELENA VLADIČIĆ-MAŠIĆ, DRAGANA JOKANOVIĆ, SRĐAN MAŠIĆ, SLAĐANA POPOVIĆ, OLIVERA ČANČAR