CDK4/6 inhibitors in HR‑positive/HER2‑negative breast cancer: a scoping review of randomised clinical trials
Introduction. Breast cancer is the most common malignancy in women and a leading cause of cancer mortality. The HR-positive/HER2-negative subtype accounts for most cases and is characterized by initial endocrine sensitivity followed by resistance. This study aimed to map and interpret randomized clinical trial evidence on the efficacy and safe...
By Sanja Stojanović Gagović, Nikolina Dukić, Jelena Vladičić Mašić, Dragana Stupar, Nemanja Kovač, Snežana Zečević
Inhibition of neutrophil oxidative burst and NETosis by fullerene-like inorganic tungsten disulfide nanoparticles with preservation of cell viability
Introduction. Tungsten disulfide (WS₂) nanoparticles possess unique physicochemical properties, making them promising candidates for biomedical applications. While previous studies have demonstrated the in vitro biocompatibility of WS₂ in various cell lines, their effects on neutrophil function remain unexplored.Methods. Human neutrophils were isol...
By Snežana Zečević, Darinka Popović, Sara Rakočević, Vanja Mališ, Ljiljana Jojić, Marija Drakul, Dušan Mihajlović, Miodrag Čolić
Numerical areal density of CD34 and CD117 immunoreactive hematopoietic cells in human fetal and embryonic liver
Introduction. Hematopoiesis is the process of developing blood cells and the formed elements of blood. This dynamic process occurs postnatally in the bone marrow, while the prenatal hematopoiesis is scattered over multiple localizations. It begins in the yolk sac, in the intra-embryonic islands of hematopoiesis, and continues in the liver, spleen, ...
By Jelena Vladičić-Mašić, Ivan Nikolić, Vera Todorović, Marko Jović, Vladimir Petrović, Srđan Mašić, Nikolina Dukić, Snežana Zečević