Introduction. Extramural venous invasion (EMVI) is a significant predictive factor of the prognosis for patients with colorectal carcinoma and it is directly connected with the relapse of a disease, especially with the appearance of distant metastases. Methods. The research comprises 90 patients with colorectal cancer. Representative samples of tum...

By Mirjana Ćuk, Slavica Knežević Ušaj, Ištvan Klem, Radoslav Gajanin, Danijela Batinić Škipina, Radmil Marić, Sanja Marić, Nenad Lalović, Nikolina Dukić

Introduction. The Bcl-2 gene codes an oncoprotein, inhibits a programmed cell death or apoptosis and it plays a very important role in colorectal cancerogenesis. The aim of our study is to determine Bcl-2 expression in colorectal carcinomas in relation with the stage of disease, histology of tumor type, localization and macroscopic growth pattern. ...

By Danijela Batinić Škipina, Slavica Knežević Ušaj, Dragana Zec, Mirjana Ćuk, Snežana Božanić, Nenad Lalović