Introduction. Peripheral arterial disease (PAD) is a progressive, occlusive and atherosclerotic vascular disease and patients with type 2 diabetes mellitus (DM) are at increased risk of developing this disease. The aim of the study was to determine the frequency of PAD in patients with type 2 DM by measuring the ankle-brachial index (ABI) in the fa...

By Biljana Lakić, Saša Turajlić, Verica Petrović

Myocarditis is a limited or diffuse inflammation of the heart muscle, the cause of which might be infectious (viruses, bacteria, fungi, rickettsiae, parasites, protozoas) or non-infectious (systemic diseases, metabolic diseases, toxins). There are types of myocarditis the etiological factor of which cannot be determined and therefore are classified...

By Tatjana Gavrilović-Elez, Vladimir Čančar, Nada Avram, Biljana Milinković, Dejan Bokonjić

Introduction. Anemia is an important public health problem recognized worldwide either as an isolated problem or associated with other forms of malnutrition. In 2016, the prevalence of anemia in women of reproductive age was 32.0%, that is 613 millions of women, aged 15-49 years. The aim of the present study was to determine the prevalence of anemi...

By Dragana Stojisavljević, Slađana Šiljak, Ljiljana Stanivuk, Jelena Niškanović, Marin Kvaternik

Introduction. Hematopoiesis is the process of developing blood cells and the formed elements of blood. This dynamic process occurs postnatally in the bone marrow, while the prenatal hematopoiesis is scattered over multiple localizations. It begins in the yolk sac, in the intra-embryonic islands of hematopoiesis, and continues in the liver, spleen, ...

By Jelena Vladičić-Mašić, Ivan Nikolić, Vera Todorović, Marko Jović, Vladimir Petrović, Srđan Mašić, Nikolina Dukić, Snežana Zečević

Introduction.Voice is the result of vocal cord vibrations and resonance effects of the vocal tract, therefore, the instrumental monitoring of the vibrations themselves is one of the essential aspects of objective instrumental assessment of voice. Inadequate height and volume, as well as increased nasality, represent the basic characteristics of voi...

By Slađana Ćalasan, Nadica Jovanović-Simić, Snežana Babac, Mirjana Petrović-Lazić

Introduction. Aggressive behavior is defined as the behavior of such intensity, frequency and duration that it seriously threatens the physical safety of a person/persons or the one which seriously limits their social functioning. The aim of the paper is to determine the intensity and forms of aggression in institutionalized women with intellectual...

By Bojana Mastilo, Bojana Vuković, Stevan Šeatović, Sladjana Ćalasan

The human epidermal growth receptor 2 (HER2, c-erb-B2) is present in 15-20% of breast cancer at the time of diagnosis. Overexpression of HER2 receptor is associated with more aggressive form of breast cancer. Trastuzumab is a human monoclonal antibody that blocks the signaling pathways of cell proliferation by binding to the HER2 receptor. Due to t...

By Dragana Jokanović, Slađana Popović, Olivera Čančar, Nikolina Dukić, Zdenka Gojković, Nenad Lalović, Jelena Vladičić Mašić, Srdjan Mašić

Introduction. The optic nerve is supplied by the arterial branches of the supericial pial plexus and direct intraneural branches. The aim of the study was to study the morphological characteristics (origin, number of arteries, calibers, and branching pattern) of perioptic arterial vascularization and intraoptic vascular network of the extracranial ...

By Radmila Balaban-Đurević, Samra Hajrović, Vanja Pljevaljčić, Valvita Reçi, Stefan Kulić, Milan Milisavljević, Siniša Šolaja

Introduction. Burnout syndrome is a common problem among healthcare workers. The aim of the study was to investigate the level of stress, components of burnout syndrome and the most common causes of workplace stress among the physicians working in the Primary Health Care Center Banja Luka, after which the obtained results concerning family physicia...

By Brankica Marković, Kosana Stanetić, Verica Petrović, Bojan Stanetić

Introduction. Secondary failure to treatment with oral antidiabetic agents is defined as the absence of a favorable reaction to the oral therapy which had proved effective in the previous course of the treatment. The aim of the study is to investigate the residual effects of the short-term combination therapy with insulin on glycoregulation and ins...

By Aleksandra Grbić, Gabrijela Malešević, Slavko Grbić, Milorad Grujičić, Vesna Jelača