Metformin-associated hepatotoxicity: a literature review
Metformin (dimethyl biguanide) is an oral antidiabetic agent and one of the most commonly prescribed medications in endocrinology. In addition to its primary use in treating type 2 diabetes, it has a broader range of indications and is generally considered to have a favorable safety profile. The most common side effects are gastrointestinal, includ...
By Goran Bokan, Zoran Mavija
Evolution of hospitalized COVID-19 cases with emphasis on the first pandemic year: experience from the University Clinical Center of Republic of Srpska
Introduction. Infection caused by the novel coronavirus (SARSCoV-2) emerged in 2019 in China and rapidly spread worldwide. This highly contagious virus is transmitted primarily through respiratory droplets and may lead to Severe Acute Respiratory Syndrome (SARS). The World Health Organization (WHO) declared Coronavirus Disease 2019 (COVID-19) a glo...
By Nataša Janjić, Goran Bokan, Uroš Kalajdžić, Antonija Verhaz, Slavica Zeljković, Zoran Mavija
CLIF-C AD score versus MELD score in predicting mortality in alcoholic liver cirrhosis patients
Introduction. Alcoholic liver cirrhosis is an advanced stage of progressive liver failure with an often adverse outcome. Numerous scoring systems are used to predict outcomes. The results of MELD Score (Model For End-Stage Liver Disease) and CLIF Consortium Acute Decompensation score (CLIF-C ADs) were used in this paper to determine which one is mo...
By Goran Bokan, Zoran Mavija