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30.06.2022.

Original Scientific Articles

Magnetic resonance imaging of the heart as a method of long-term monitoring of right heart function after tetralogy of Fallot surgery

By Biljana Milinković, Jelena Milić, Dejan Bokonjić, Verica Prodanović, Bojan Joksimović, Siniša Ristić

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Edited by:

Prof. Siniša Ristić MD, PhD

Vol 15, No 1 (2024):

Biomedicinska istraživanja

Published: 18.11.2024.

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17.12.2024. Case Reports Online First
Medial fibular transport with the Ilizarov apparatus in the treatment of infected tibial pseudarthrosis

By Maksim Kovačević, Marijana Kovačević, Verica Prodanović, Sanja Marić, Nada Avram , Aleksandar Tanović, Dražen Erić

Introduction. Tibial bone defects, particularly those caused by infections, represent one of the most complex challenges in orthopedics. Given the severity of complications such as limb function loss or even amputation, the need for innovative and reliable treatment methods is crucial. Medial fibular transport using the Ilizarov apparatus offers a successful solution to these problems, preserving limb functionality and integrity.
Case report. This paper presents the case of a 76-year-old patient with chronic osteomyelitis and infected tibial pseudarthrosis. Following radical debridement and sequestrum removal, a significant partial bone defect measuring 8 cm remained. Treatment was performed using medial fibular transport with the Ilizarov apparatus. The reconstruction process lasted eight months, after which complete bone consolidation, infection elimination, and restoration of limb function were achieved.
Conclusion. The medial fibular transport technique has proven to be an effective and safe method for treating large tibial defects associated with infection, enabling limb preservation and significantly improving patients’ quality of life.

17.12.2024. Original Scientific Articles Online First
Correlation between skin and clinical features in systemic sclerosis

By Ljubinka Božić Majstorović, Snježana Popović Pejičić, Irma Ovčina, Verica Ivanović Prodanović, Jelena Mrdja

Introduction. Systemic sclerosis (SS) is a complex autoimmune disease characterized by chronic progressive organic sclerosis. The aim of this paper is to show the correlation of ultrasound (US) parameters with Rodnan skin score (mRSS), as well as the clinical involvement of other organ systems. 
Methods. Our study included 24 patients diagnosed with SS and 24 healthy controls. We included demographic, clinical and laboratory parameters, individually and included in the European Scleroderma Trial and Research Disease Activity Index (EUSTAR-DAI) score. To measure skin involvement, we used the modified mRSS and skin ultrasound.
Results. The skin thickness of patients and healthy controls measured by ultrasound showed statistically significant differences (p<0.001). Correlations between mRSS and anti-Scl-70 antibody (p=0.02) and between mRSS and diffusion capacity for carbon monoxide (DLCO) (p=0.03) were shown.
Conclusion. In recent years, the importance of using skin ultrasound in patients with systemic sclerosis has been increasing, due to the fact that this technique can detect skin involvement in the early stages of the disease. The advantages of the method are availability and non-invasiveness, unlike skin biopsy. By standardizing ultrasound skin measurement, it would be possible to implement the method in daily clinical practice.

17.12.2024. For Practice Online First
Robotic colorectal surgery: experiences, challenges and opportunities through our own research

By Igor Černi, Dragan Vanovac

Robotic colorectal surgery has revolutionized minimally invasive surgical techniques, offering numerous advantages over traditional approaches. Enhanced precision, reduced blood loss, shorter hospital stays, and improved patient outcomes are among the key benefits. However, high costs and technical complexities limit its widespread adoption.
This study explores the experiences, challenges, and future directions of robotic colorectal surgery. While it offers significant advantages, further research is needed to optimize techniques, reduce costs, and expand its application. By addressing technical limitations and exploring innovative approaches, robotic surgery has the potential to further improve patient care and surgical outcomes.

06.12.2024. Original Scientific Articles Online First
The effect of socio-demographic characteristics on the burnout syndrome of nurses in Republic of Srpska during the COVID-19 pandemic

By Ljubiša Kucurski, Tamara Popović, Dijana Djurić, Jelena Pavlović, Ljiljana Savić, Srdjan Živanović, Ljubinka Božić Majstorović, Sanja Tomić

05.12.2024. Original Scientific Articles Online First
Stress in parents of children with developmental disabilities

By Andrijana Bakoč, Olivera Kalajdžić, Ranka Perućica, Ivana Zečević

26.11.2024. Reviews Online First
Anatomy of the vertebral vein

By Slobodan Malobabić

26.11.2024. Original Scientific Articles Online First
Awareness of the general population about vocal voice hygiene

By Violeta Bilinac, Ana Lončar

04.11.2024. Original Scientific Articles Online First
The effect of glucoregulation on hearing loss in patients with diabetes mellitus type 2

By Mirjana Gnjatić, Dalibor Vranješ, Tamara Dojčinović, Jelena Malinović Pančić, Boris Dojčinović

28.12.2019. Original Scientific Articles
Impact of elapsed time between first symptoms and diagnosis of celiac disease on psycho-physical functioning and social life of children and adolescents

By Biljana Stojanović-Jovanović, Stevan Jovanović, Biljana Vuletić

Introduction. Celiac disease is an autoimmune disease resulting from an inadequate immune response to gluten in genetically predisposed individuals as a result of consuming gluten and other related proteins present in wheat, rye, barley and oats. The only cure for this specific disease is a strict, carefully controlled and lifelong gluten-free diet. The aim of the study was to evaluate whether the elapsed time between the onset of the first symptoms and the diagnosis of celiac disease affected the psycho-physical functioning and social life of children and adolescents.

Methods. The study involved 116 respondents (39 of them were males), aged 8-18 years, who were diagnosed with celiac disease. The Documentation Sheet and the Celiac-Specific Pediatric Health-Related Instrument (CDPQOL), measuring the psycho-physical functioning and social life, were used in the study.

Results. 50% of subjects, aged ≤ 2 years, were diagnosed with celiac disease. 48.28% of them were diagnosed with the disease within three months after the symptom onset. In respondents with celiac disease, aged 8-12 years, there was no statistically significant difference between the psycho-physical functioning and social life and the elapsed time between the first symptoms and the established diagnosis. In subjects aged 13-18 years, using CDPQOL, a statistically significant difference was found in the following domains: school functioning, going out and social events, self-confidence. Furthermore, there was a statistically significant difference between total CDPQOL score and the elapsed time between the first symptoms and the established diagnosis.

Conclusion. The elapsed time between the first symptoms and the established diagnosis significantly affects the psycho-physical functioning and social life of subjects aged 13-18 years, but it does not affect the psycho-physical functioning and social life of the younger respondents. This is to confirm the importance of early diagnosis and treatment initiation.

Current issue
18.11.2024. Original Scientific Articles
Relationship between perceived stress and levels of blood pressure: single center study

By Milena Guslov, Marko Filipović, Danijela Tasić, Sladjana Božović Ogarević, Biljana Despotović, Zorana Bogićević, Milan Arsić, Svetislav Pelemiš, Maša Petrović, Zlatko Maksimović, Nebojša Tasić

18.11.2024. Reviews
The transformative power of AI and wearables in the global prevention of cardiovascular disease

By Maša Petrović, Svetislav Pelemiš, Ana Dimitrijević, Srdjan Babić, Sulin Bulatović, Nebojša Tasić, Danijela Tasić, Zorana Bogićević, Sladjana Božović-Ogarčević, Milan Arsić, Marko Filipović, Milena Guslov, Branko Lozuk, Zlatko Maksimović, Milovan Bojić

Recent issues
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01.12.2011. Original Scientific Articles
Dijagnostika fokalnih promjena u jetri

By Zoran Terzić, Branko Brmbolić, Miloš Korać, Boban Đorđević, Dragica Terzić, Bogdanka Andrić, Siniša Ristić

Uvod. Patološki procesi u jetri mogu biti difuznog karaktera (zapaljenski,metaboličke bolesti, hematološke bolesti, toksične bolesti) i fokalne (zapaljenske,parazitarne i tumorske). Cilj rada je prikaz fokalnih promjena u jetrinomparenhimu nakon ultrazvučne, laparaskopske i patohistološke dijagnostike.Metode. Retrospektivno-prospektivnim ispitivanjem je obuhvaćeno 147punoljetnih pacijenata oba pola. Fokalne promjene jetrinog tkiva su sagledaneultrazvučnom, laparoskopskom i patohistološkom dijagnostikom.Rezultati. Osnovne karakteristike ispitanika: muškaraca 71 i žena 76 sanajvećim brojem pacijenata (102 - 70%) životne dobi između 40 i 70 godina,sa ravnomjernom distribucijom za svakih deset godina starosti. Međutim,neobično je veliki broj pacijenata ženskog pola registrovan u četvrtoj decenijiživota, čak 14 (9,5%) od ukupnog broja ispitanika, odnosno 18% odispitanika ženskog pola. Metastaze čine 104 (71%) svih fokalnih lezija jetre.U većini slučajeva radilo se o metastazama karcinoma dojke. Iako najčešćeimaju tipičnu ultrazvučnu prezentaciju, metastaze u jetri mogu da daju širokspektar različitih ultrazvučnih slikaZaključak. Najčešće fokalne promjene u jetri su metastaze adenokarcinoma.Samo 3 (2%) fokalne promjene dijagnostikovane ultrazvukom nisu potvrđenekao fokalne laparoskopskom tehnikom i patohistološkom analizom tkiva jetre.

30.06.2022. Original Scientific Articles
Voice condition assessment and the effect of rehabilitation in vocal professionals

By Mila Bunijevac, Zlatko Maksimović, Andrijana Mikić

01.12.2012. Original Scientific Articles
Sensibility of tactile discrimination between the fingers of the dominant and non-dominant hands

By Olivera P Spasojević, Zoran Obradović, Slavko Grbić, Marinko Domuzin, Aleksandra Grbić

28.06.2021. Reviews
Vitamin D and atherosclerosis

By Olivera Rašević, Maida Mulić, Maja Vuković, Vesna Lazić, Biljana Mijović, Miloš Maksimović

28.06.2021. Original Scientific Articles
The knowledge of nurses about prevention of infections caused by the bacteria Clostridium difficile

By Ivana Miljković, Amajla Topuz

Introduction. Clostridium difficile is the leading cause of nosocomial diarrhea, associated with the use of antibiotics. The most common ways of transmitting the infection in hospitals are contaminated surfaces of the premises and the hands of medical staff. Methods. The study involved 68 nurses/technicians employed at the University Hospital Foca in the departments of surgery and internal medicine. As a research instrument, we used a specially designed questionnaire, created by the authors for the purpose of this research. Results. The research showed that 61.8% of respondents knew that hand washing with warm water and soap was considered the most effective prevention of the spread of infections, and 55.88% meant that they used chlorine-based preparations and hydrogen peroxide as the only effective disinfectant. Nurses with a work experience of less than 5 years showed better knowledge than other groups. Conclusion. The knowledge of nurses about the prevention of C. difficile infection is not at a satisfactory level, which indicates the growing need for education of nurses.

30.06.2022. Original Scientific Articles
Magnetic resonance imaging of the heart as a method of long-term monitoring of right heart function after tetralogy of Fallot surgery

By Biljana Milinković, Jelena Milić, Dejan Bokonjić, Verica Prodanović, Bojan Joksimović, Siniša Ristić

28.12.2019. Original Scientific Articles
Impact of elapsed time between first symptoms and diagnosis of celiac disease on psycho-physical functioning and social life of children and adolescents

By Biljana Stojanović-Jovanović, Stevan Jovanović, Biljana Vuletić

28.12.2020. Reviews
Importance of documentation in nursing practice

By Amajla Topuz, Ivana Miljković

01.12.2015. Case Reports
Faktori koji utiču na ishod liječenja sindroma kaude ekvine

By Zorislava Bajić, Milada Nalesnik, Tatjana Boškić, Biljana Jovanović, Tatjana Bućma

Uvod. Grupa znakova i simptoma koji se javljaju kao rezultat oštećenja nervnihkorjenova caudae equinae smještenih u kičmenom kanalu nosi naziv sindromkaude ekvine (cauda equina syndrome). Najčešće je uzrokovana lumbalnomhernijacijom intervertebralnog diska. Klinička slika se karakteriše bolom ukrsnom, glutealnom i perinealnom regionu, bolom duž zadnje strane donjegekstremiteta, utrnulošću i motornim i senzornim deficitima na donjim ekstremitetima.Može se javiti i disfunkcija mokraćne bešike i potencije.Prikaz bolesnika. Pacijent dolazi na pregled kod fizijatra zbog jakog bola uslabinskom segmentu, koji se propagirao duž oba donja ekstremiteta praćenosjećajem slabosti, više lijevo, te nemogućnosti pražnjenja mokraćne bešike.Snimak dobijen nuklearnom magnetnom rezonancom (NMR) pokazujeprotruziju intravertebralnog diska na dva nivoa. Pacijent je podvrgnut operativnomzahvatu: Hemilaminectomia L4 l. sin et foraminotomia L5-S1 l. sin,extirpatio disci. Mjesec dana nakon operativnog zahvata provodi postoperativnustacionarnu rehabilitaciju. Na prijemu je detektovana slabost plantarnihfleksora lijevog stopala, te trnjenje u istom, nepotpuno pražnjenje bešike,nemogućnost kontrole spoljašnjeg analnog sfinktera i disfunkcija potencije.Nalaz urofloumetrije potvrdio je tešku hipotoniju detrusora mokraćne bešikekoja graniči sa atonijom. Pacijent je proveo fizikalni tretman, te dva ciklusaelektrostimulacije detrusora mokraćne bešike. Kontrolni urodinamski nalazbez značajnijih promjena u odnosu na prethodni. Nakon provedenog liječenjapacijent ima osjećaj olakšanog mokrenja, seksualna disfunkcija je manjа, snagaplantarnih fleksora je poboljšana.Zaključak. Na samom početku liječenja bili su prisutni faktori koji su ukazivalina teškoće u ishodu liječenja (hronični bol, odloženo operativno liječenje,odložena rehabilitacija). Smatramo da je poboljšanje nastupilo kao posljedicapsihološkog stanja pacijenta koji uspijeva uticati na aktivnosti sfinktera.

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